ID A0A498K0W6_MALDO Unreviewed; 502 AA.
AC A0A498K0W6;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273};
DE EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};
GN ORFNames=DVH24_015149 {ECO:0000313|EMBL:RXI01800.1};
OS Malus domestica (Apple) (Pyrus malus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX NCBI_TaxID=3750 {ECO:0000313|EMBL:RXI01800.1, ECO:0000313|Proteomes:UP000290289};
RN [1] {ECO:0000313|EMBL:RXI01800.1, ECO:0000313|Proteomes:UP000290289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. HFTH1 {ECO:0000313|Proteomes:UP000290289};
RC TISSUE=Young leaf {ECO:0000313|EMBL:RXI01800.1};
RA Hu J.;
RT "A high-quality apple genome assembly.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|RuleBase:RU004273};
CC -!- SIMILARITY: Belongs to the PPP phosphatase family.
CC {ECO:0000256|RuleBase:RU004273}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXI01800.1}.
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DR EMBL; RDQH01000330; RXI01800.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498K0W6; -.
DR STRING; 3750.A0A498K0W6; -.
DR EnsemblPlants; mRNA:MD04G0161400; mRNA:MD04G0161400; MD04G0161400.
DR Gramene; mRNA:MD04G0161400; mRNA:MD04G0161400; MD04G0161400.
DR Proteomes; UP000290289; Chromosome 4.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; IEA:UniProt.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd07414; MPP_PP1_PPKL; 1.
DR Gene3D; 3.100.10.10; -; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR021131; Ribosomal_uL15/eL18.
DR InterPro; IPR036227; Ribosomal_uL15/eL18_sf.
DR InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR InterPro; IPR031675; STPPase_N.
DR PANTHER; PTHR11668; SERINE/THREONINE PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR11668:SF429; SERINE_THREONINE-PROTEIN PHOSPHATASE PP1 ISOZYME 9; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF17135; Ribosomal_L18; 1.
DR Pfam; PF16891; STPPase_N; 1.
DR PRINTS; PR00114; STPHPHTASE.
DR SMART; SM00156; PP2Ac; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF52080; Ribosomal proteins L15p and L18e; 1.
DR PROSITE; PS00125; SER_THR_PHOSPHATASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU004273};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000290289};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980}.
FT DOMAIN 123..128
FT /note="Serine/threonine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS00125"
FT REGION 465..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..502
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 502 AA; 56603 MW; C292C97F7CD0B553 CRC64;
MMMTMEGMMD KGVLDDIIRR LLEGKGGKQV QLSEAEIRQL CVNARQIFLS QPNLLEVRAP
VRICGDIHGQ YQDLLRVFEY GGYPPSANYL FLGDYVDRGK QSLETICLLL AYKIRYPDKI
FLLRGNHEDA KINRIYGFYD ECKRRFNVRL WKIFTECFNC LPVAALIDGK ILCMHGGLSP
ELENLDQIKE ISRPTDIPDN GLLCDLLWSD PDARVEGWAE SDRGVSCTFG ADRVSDFLDK
NELDLICRGH QVVEDGYEFF AKRRLVTIFS APNYGGEFDN AGALLSVDEA LVCSFEILKP
VDHKASPSGS KLNLKKGIDL VAGGKSKKTK RTAPKSDDIY LKLLVKLYRF LVRRTASKFN
AVILKRLFMS KVNKAPLSLS RLIKYMQGKD NKIAVVVGTI TDDIRVYEVP QMKVTALRFT
ETARARIEKA GGECLTFDQL ALRAPLGQNV VLLRGPKNSR EAVKHFGPAP GVPHSHTKPY
VRSKGRKFEK ARGKRNSKGF RV
//
