ID A0A498K3D3_MALDO Unreviewed; 614 AA.
AC A0A498K3D3;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=DVH24_015227 {ECO:0000313|EMBL:RXI01878.1};
OS Malus domestica (Apple) (Pyrus malus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX NCBI_TaxID=3750 {ECO:0000313|EMBL:RXI01878.1, ECO:0000313|Proteomes:UP000290289};
RN [1] {ECO:0000313|EMBL:RXI01878.1, ECO:0000313|Proteomes:UP000290289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. HFTH1 {ECO:0000313|Proteomes:UP000290289};
RC TISSUE=Young leaf {ECO:0000313|EMBL:RXI01878.1};
RA Hu J.;
RT "A high-quality apple genome assembly.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 28 family.
CC {ECO:0000256|ARBA:ARBA00006962}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXI01878.1}.
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DR EMBL; RDQH01000330; RXI01878.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498K3D3; -.
DR STRING; 3750.A0A498K3D3; -.
DR EnsemblPlants; mRNA:MD04G0170400; mRNA:MD04G0170400; MD04G0170400.
DR Gramene; mRNA:MD04G0170400; mRNA:MD04G0170400; MD04G0170400.
DR Proteomes; UP000290289; Chromosome 4.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR007235; Glyco_trans_28_C.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR47989; OS01G0750732 PROTEIN; 1.
DR PANTHER; PTHR47989:SF2; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF04101; Glyco_tran_28_C; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000290289};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 214..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 315..591
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 595..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 343
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 614 AA; 67609 MW; 705271D307DB611C CRC64;
MGDSEVNVKA QKTVFVTVGT TSFDALVRAV DTHEFKEELS KRGYTRLLIQ MGRGSYIPTK
PEGGGEPLAV DYFTFSSSIA DHLRAASLVI SHAGSGSIFE TLRLGKPLIV VVNEDLMDNH
QSELAEELAD RKHLYYGRPQ TLHHVVADMN LDSLVPYHPG DATPVAKLIN RFLVNTTAAA
SAGPLDLAAK NHTHKHQPYS HHQHHQGNFP SKSVLIIIIS IISVMALLAI IFIVLMLRRL
VKSTKTNGNI YKENTGLINT SCRSIAQTAV DFNSSPDVKG GCLQGGNSGR PLKAPADKGV
QVFSYKELEE ATDKFSEANV IGHGGFGVVY KGVLRDGTVA AIKMLRREGR QGERAFRFEV
DLLSRLHSPY LVELLGYCAD QHHRLLIFEC MPHGTLQRHL HPTNNHQPLD WGTRLRIALD
CAEALEFLHE HAIPSVIHRD FKCSNVLLDQ NFRAKVSDFG LAKMGSDKIN GQISTRVLGT
TGYLAPEYAS TGRLTTKSDV YSYGVVLLEL LTGRVPVDTK RPPGEHVLVS WALPRLTNRE
KVLEMVDPAL QGQFSKRDLI QIAAIAAMCV QPEAEYRPLM TDVVPSLIPL VQNSSYGASS
GSSRFHNQIP SPRC
//
