ID A0A498KC49_MALDO Unreviewed; 689 AA.
AC A0A498KC49;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Histone-lysine N-methyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=DVH24_006355 {ECO:0000313|EMBL:RXI05098.1};
OS Malus domestica (Apple) (Pyrus malus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX NCBI_TaxID=3750 {ECO:0000313|EMBL:RXI05098.1, ECO:0000313|Proteomes:UP000290289};
RN [1] {ECO:0000313|EMBL:RXI05098.1, ECO:0000313|Proteomes:UP000290289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. HFTH1 {ECO:0000313|Proteomes:UP000290289};
RC TISSUE=Young leaf {ECO:0000313|EMBL:RXI05098.1};
RA Hu J.;
RT "A high-quality apple genome assembly.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00358}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXI05098.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; RDQH01000328; RXI05098.1; -; Genomic_DNA.
DR RefSeq; XP_008346233.1; XM_008348011.2.
DR RefSeq; XP_008346239.1; XM_008348017.2.
DR AlphaFoldDB; A0A498KC49; -.
DR STRING; 3750.A0A498KC49; -.
DR EnsemblPlants; mRNA:MD02G0223400; CDS:MD02G0223400.1; MD02G0223400.
DR GeneID; 103409193; -.
DR Gramene; mRNA:MD02G0223400; CDS:MD02G0223400.1; MD02G0223400.
DR KEGG; mdm:103409193; -.
DR OrthoDB; 5481936at2759; -.
DR Proteomes; UP000290289; Chromosome 2.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 2.30.280.10; SRA-YDG; 1.
DR InterPro; IPR025794; H3-K9-MeTrfase_plant.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR007728; Pre-SET_dom.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR036987; SRA-YDG_sf.
DR InterPro; IPR003105; SRA_YDG.
DR PANTHER; PTHR45660; HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR; 1.
DR PANTHER; PTHR45660:SF73; HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH1; 1.
DR Pfam; PF05033; Pre-SET; 1.
DR Pfam; PF02182; SAD_SRA; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00468; PreSET; 1.
DR SMART; SM00317; SET; 1.
DR SMART; SM00466; SRA; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50867; PRE_SET; 1.
DR PROSITE; PS51575; SAM_MT43_SUVAR39_2; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS51015; YDG; 1.
PE 4: Predicted;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00358}; Reference proteome {ECO:0000313|Proteomes:UP000290289};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 224..374
FT /note="YDG"
FT /evidence="ECO:0000259|PROSITE:PS51015"
FT DOMAIN 449..510
FT /note="Pre-SET"
FT /evidence="ECO:0000259|PROSITE:PS50867"
FT DOMAIN 513..658
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 673..689
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 67..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 689 AA; 75685 MW; 461EF5C74D62A79B CRC64;
MEGGSSQNFV PPSAGFDKSR VLDVRPLRSL MPVFPAASQA PSFPGMPPFG NTPNGFPPFY
PFGLPSSYQA SPDLNSEMRT PTGPMPAPIR SYRAPTSSGA DDFPEDSNGD GYFDPHVGSS
SSRKKTTKAS SSRKKTKKNG DGDSLTNNGS GVTFVSAMSS FQIEDGNREL VNYVLMNFDA
LRRRICQIED NKESKTGVIK RADLKAGGIV MSKKVRTNMR RRVGVIPGVE IGDIFFFRME
MCAVGLHAPS MAGIDYMTGN GDGDKDPVAL SIVSSGGYDD EAEASDVLIY SGQGGNSNSK
DKDREVADQK LERGNLALQR SLHHGNEVRV IRGVKDDVSS TIKIYVYDGL YKVHESWTER
GKAGCNIFKY KLLRVPGQPP AFAVWQAIRK WKDGFSSRAG LVLQDLTSGT EPVPVSLVNE
VDNEKALVSF TYFPTLKYTK SFSLMPPSFG CNCRSACQPG DTNCSCIQKN GGDFPYTSNG
ILVSRKQLLH ECGPTCPCTP NCKNRVSQTG VKLRLEVFKT KDRGWGLRSW DSIRAGAFIC
EYAGEVIDEA KLKQKEDGGE NDEYIFDTGR DYESFKWSYE PGLIEESPND VEDYNIPYRL
IISAKNVGNV GRFINHSCSP NVFWQPVVYE HNNQSFVHIA FYAIGHIPPM TELTYDYGSS
SSNEAGSNSG PNRKNKCLCG SSKCRGYFG
//
