ID A0A498L8U7_LABRO Unreviewed; 1381 AA.
AC A0A498L8U7;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Caskin-2-like isoform X3 {ECO:0000313|EMBL:RXN04652.1};
GN ORFNames=ROHU_033854 {ECO:0000313|EMBL:RXN04652.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN04652.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN04652.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN04652.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN04652.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN04652.1}.
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DR EMBL; QBIY01013431; RXN04652.1; -; Genomic_DNA.
DR STRING; 84645.A0A498L8U7; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd09497; SAM_caskin1_2_repeat1; 2.
DR CDD; cd09498; SAM_caskin1_2_repeat2; 2.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 4.
DR InterPro; IPR033635; ANKS1/Caskin.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR032232; Caskin1-CID.
DR InterPro; IPR035497; Caskin1/2_SAM_1.
DR InterPro; IPR035498; Caskin1/2_SAM_2.
DR InterPro; IPR032117; Caskin_C.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR PANTHER; PTHR24174; ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR24174:SF18; CASKIN-2; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF16907; Caskin-Pro-rich; 1.
DR Pfam; PF16632; Caskin-tail; 1.
DR Pfam; PF16600; Caskin1-CID; 1.
DR Pfam; PF00536; SAM_1; 4.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 7.
DR SMART; SM00454; SAM; 4.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 4.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 5.
DR PROSITE; PS50105; SAM_DOMAIN; 4.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 48..80
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 81..113
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 114..146
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 182..214
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 214..236
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 463..526
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 532..581
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 609..672
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 678..742
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 323..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 806..865
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 891..911
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 925..1142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1195..1216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1230..1271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 815..865
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 925..982
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 989..1027
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1051..1088
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1109..1142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1230..1245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1381 AA; 149869 MW; 4E0B9831A279C4D5 CRC64;
MGKEQDLLLA VKNGDLPLAH KLLAKIKTNR NKLLGSTKRL NVNYQDQDGF SALHHAALTG
TTDLLSLLLE AQATVDIKDS NGMRPLHYAA WQGKADSVLM LLRAGASVNG ASQDGQIPLH
LAAQYGHYEV SEMLLQHQSN PCTVNKAKKT PLDLACEFGR LKVTQLLLSS NMVVALLEGN
GRDNTPLHLA ARNGHKDIIR LLLKAGIDIN RTTKSGTALH EAALYGKMEV VKLLLDVLEQ
HMDGRWKGHI HDSQRGTDRV GFFPPSIVEV ISRRSGGVLS RQASLPIQRH HILSRALSLH
SSQHTSHTDD SYTLYSSTRP VLTHHNGLDQ HPGALPDSPS ALCKPASPKE PEDIWVLRTS
LNAGDRNSVG SAGSMGSSRS AGSGQSTEGN FPHNGPNQSP SAVQDTTKLP PSAGELVEHC
SQAPDTTKQT DPYSGALGRR IPLSSSRLGE HHVIHSQQIL DGKDAEAIYQ WLCEFQLEQY
TSNFLTAGYD VPTISRMTPE DLTAIGVTKP GHRKKISMEI GNMNIPEWLP DYIPSDIGKW
LSAIGLPQYQ KKLAENGYDS ISIVQDITWE DLQEIGITKL GALGRRIPLS SSRLGEHHVI
HSQQILDGKD AEAIYQWLCE FQLEQYTSNF LTAGYDVPTI SRMTPEDLTA IGVTKPGHRK
KISMEIGNMN IPEWLPDYIP SDIGKWLSAI GLPQYQKKLA ENGYDSISIV QDITWEDLQE
IGITKLGHQK KLMLAVKKLS DVQKARKSQA EGQALLQHRR APPALELVAI EHHDNSECPS
SPLSPKMLTF QDSELSIELQ NAMARSGYGG GQDGLGSMSG TTMRLSQESI GTRSGGSGRS
QERPMASVSP NSRSQESLGS MDNSPNKEQY AIMESQDRSQ ISPVKMAPVL PLQHHHPSSG
SPARTPPITT SKIARFAYPP VLTKTRPVVS SSQPHHGSPT QRGFNYLQHQ NMGSPSPVRA
PQPNGDTSRS KKRTQSLSRY AMSDGENEDD ISAPTTTTVN VASYATLTRK PGRSQPSYTS
SERQVGRSHS FAIRAKRKGP PPPPPKRLSS APSGVTRSGV ETESAGSVRS IAARLENNTG
SPDKTCNSPV FKAMSPVISP KNMENRRRTA SESSTYQTKH TTGENISPLR NQQGSTSSQE
SIPFAEEGKV TIKQRTKIAA AKIESEAGVE ILKSAQSIKS SLEVPEFNLK ESDTVKRRHK
PKELQTKGQG ASTQIGNERA AETGMVSQCM QNGGLTKNPY KSGLSLNPGS PHKPPTPSKP
TRHSSAANSG VTVSVAQSVT FAVSPPCTPL AHCPPNKAPQ AQSVLPGNPQ AVTEGQNVLV
HKRLEQTSTS LEAALKVVEK KLAQEDPADR GINTVKSAGN ILDDIGNMFD DLADQLEAML
D
//
