ID A0A498L919_LABRO Unreviewed; 927 AA.
AC A0A498L919;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=FERM domain-containing 4B-like isoform X2 {ECO:0000313|EMBL:RXN03853.1};
GN ORFNames=ROHU_035769 {ECO:0000313|EMBL:RXN03853.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN03853.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN03853.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN03853.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN03853.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN03853.1}.
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DR EMBL; QBIY01013469; RXN03853.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498L919; -.
DR STRING; 84645.A0A498L919; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13191; FERM_C_FRMD4A_FRMD4B; 1.
DR CDD; cd17200; FERM_F1_FRMD4B; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR021774; CUPID.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR047176; FRMD4A/B.
DR InterPro; IPR041785; FRMD4A/B_FERM_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46079; FERM DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46079:SF1; FERM DOMAIN-CONTAINING PROTEIN 4B; 1.
DR Pfam; PF11819; CUPID; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT DOMAIN 5..284
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 504..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 573..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 614..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 336..373
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 453..480
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 518..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..602
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..667
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..712
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 927 AA; 106671 MW; 6CEDB5E74CDE6DAE CRC64;
MTEGRLCQVL LLDDRQLELL VQPKLLSRDL LDLVSSHFNL KEKEYFGISF IDEKGQTNWL
QLDRRVLDHD FSKKSGPLEL KFQVRFYIES VAYLKDATTV ELFFRNAKIS LYNCNESDED
TRSDLKKLPA FPTAVLKEHP SLAFCEDKVI EHYKKLKGLS RGQAIIRYLT LVESLPAYGV
HYYKVKDKQG LPWWLGVSYK GIGQYDLQDK LKPRKLFLWK QLENLYFREK KFAVEVNDPQ
RRTASRRTFG QSGQVIYTWY ASHSLIKTIW VMAISQHQFY LDRKQSKAKI TTARSLGDIA
MDLTETGAPR NSKLVSMESK DKLIMASNGS LVSSNSADNE VNEEQKKEKI AELKNKQESI
KEMLALKEEE LKKMCLREAE LTGVLPKEYP LALGEKPPTV RRRVGTAFKL DDLFPYDADP
HLRNLESCFA LQKKIVEAAK KLAYENELCK TVKKKRRRNL VDATKKLQEI ENQINDYRVK
IGKEPTQRAS VIIADDVNLD SLSDCLNLDD DEPSQRQRSR SVQYSPRPNS SNSFSASCHS
DHIDHANDDY QDCSRLNYGE VQEPVAYIHG DALSTHSSPY RQPSRQPSDS RSMPPTPQLP
RNAYSSIQLS THFRQRSGSL ESQSQFLTES EPSEPVFTIS PPRRSNSTEI LDDGSSYTSQ
SSVEYSVPGG HSRAKNRHRR RQGNIYANTG SMPNLAQNDT RGYTPQPRQQ PTTTAYYVTG
YPRYIEPEVH PNGPYMYETE MEGHYNVNPS YYRHDPHGNY GQDEIDGLAH NLYATLRPSR
TRPPSRNENI VKNMQRAEVV EHLRGWYNRQ HRQQGYDTYR APQQNMGYRT MSSNYVRSDS
TTSYSTVSSG NWHGRPVTAM SEYDMPPAHH QSYGYNTVHY SQPLHSRSYI DVNHHDSHMS
SPMDSSFDSE DQQTLYWHEN SKPGTIV
//
