ID A0A498L9Q3_LABRO Unreviewed; 146 AA.
AC A0A498L9Q3;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 {ECO:0000256|ARBA:ARBA00040285, ECO:0000256|RuleBase:RU363103};
GN ORFNames=ROHU_033580 {ECO:0000313|EMBL:RXN05091.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN05091.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN05091.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN05091.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN05091.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000256|ARBA:ARBA00003195, ECO:0000256|RuleBase:RU363103}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000256|RuleBase:RU363103}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|RuleBase:RU363103}; Peripheral membrane protein
CC {ECO:0000256|RuleBase:RU363103}; Matrix side
CC {ECO:0000256|RuleBase:RU363103}.
CC -!- SIMILARITY: Belongs to the complex I NDUFA12 subunit family.
CC {ECO:0000256|ARBA:ARBA00007355, ECO:0000256|RuleBase:RU363103}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN05091.1}.
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DR EMBL; QBIY01013420; RXN05091.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498L9Q3; -.
DR STRING; 84645.A0A498L9Q3; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:InterPro.
DR InterPro; IPR007763; NDUFA12.
DR PANTHER; PTHR12910:SF2; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 12; 1.
DR PANTHER; PTHR12910; NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2; 1.
DR Pfam; PF05071; NDUFA12; 1.
PE 1: Evidence at protein level;
KW Electron transport {ECO:0000256|RuleBase:RU363103};
KW Membrane {ECO:0000256|RuleBase:RU363103};
KW Mitochondrion {ECO:0000256|RuleBase:RU363103};
KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU363103};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A498L9Q3};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Respiratory chain {ECO:0000256|RuleBase:RU363103};
KW Transport {ECO:0000256|RuleBase:RU363103};
KW Ubiquinone {ECO:0000313|EMBL:RXN05091.1}.
SQ SEQUENCE 146 AA; 16912 MW; BCF2AFFDEF639601 CRC64;
MAEYGNLVRR AVGQLTGHGG VKGFLLQLFR VNDIKTGALV GIDKYGNKYY EDNRYFFGRH
RWVIYTTEMN GKKTLWDVDG SMVPAEWHRW LHCMTDDPPT THPPEPKKFL AKVHQFNNSG
TPNCYVPYST TRKKIHEWVP PKTGEK
//
