ID A0A498LDX6_LABRO Unreviewed; 2567 AA.
AC A0A498LDX6;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Adhesion G-coupled receptor G7-like protein {ECO:0000313|EMBL:RXN06430.1};
GN ORFNames=ROHU_012329 {ECO:0000313|EMBL:RXN06442.1}, ROHU_032837
GN {ECO:0000313|EMBL:RXN06430.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN06430.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN06430.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN06430.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN06430.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN06430.1}.
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DR EMBL; QBIY01013370; RXN06430.1; -; Genomic_DNA.
DR EMBL; QBIY01013369; RXN06442.1; -; Genomic_DNA.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 6.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR47767; ADHESION G PROTEIN-COUPLED RECEPTOR G7; 1.
DR PANTHER; PTHR47767:SF1; ADHESION G-PROTEIN COUPLED RECEPTOR G7; 1.
DR Pfam; PF00002; 7tm_2; 6.
DR Pfam; PF01825; GPS; 3.
DR SMART; SM00303; GPS; 3.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 6.
DR PROSITE; PS50221; GPS; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:RXN06430.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 665..688
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1079..1103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1115..1135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1174..1195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1207..1228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1264..1287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1308..1329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1412..1437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1449..1468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1508..1529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1541..1563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1597..1621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1642..1663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1749..1774
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1786..1805
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1845..1866
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1878..1900
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1934..1958
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1979..2000
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2084..2109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2121..2140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2178..2199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2211..2232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2268..2291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2312..2334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 103..279
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT DOMAIN 488..684
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT DOMAIN 1080..1345
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT DOMAIN 1413..1682
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT DOMAIN 1750..2019
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT DOMAIN 2085..2352
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 40..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..869
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2370..2567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..414
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 708..722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..755
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 756..787
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..803
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..835
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 836..869
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2398..2415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2416..2477
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2478..2495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2510..2527
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2537..2567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2567 AA; 292316 MW; 8ED6C0C6BDAC2BE1 CRC64;
MRSYTKDSNK WTPGVITDVT GPLSYRVRTG DGQVHRRHVD QLLDRVTPSW SPSGPEPEGY
TVSRPEPSGI ERPELQPPAM EMENPGEEIA GAESMSESPR SRRKSRGSNP TLLVVNICLS
MTVFYLLFVF GINNPVQHVN VARVSGENIV PESDHHKYRD EGPCTAFTAL LQYFLLATFT
WNTLYGINVY MLFHGSVSGT PRWFPKVCMA VGWGLPAVIV GISLASTYRV DEPLGYRQEE
FCWLASVDHK QRFSIMKPML WGFVLPLLIM LISSTAILLH FMYNICKTNP NLNSDRIEQR
HDSRAPPHNR DRTEQHHNNQ PPPHNRDHTE QHHNNQPLPH NRDHTEQRHN NQPLPHNRDH
TEQRHNNQPL PHNRDHTEQR HNNQPLPHNR DHTEQRHNNQ PLPHNRDHTE QHHNNQPPPH
NSTESGFNEN IGFVLYDNDQ FFQSKSFQPS LDTKRRVISA NLEENPEIVQ FTVSPSAYDI
NYNYSKALDW ISITGCALSV LGLCATALYQ IRTRKSRGGN PTLLVVNICL SMTVFYLFFI
FGINNPVEHP IEREVSGENI VPESDHHKYP DQGPCTAFTA LLQYFLLATF TWNTLYGINV
YINETPRWFP KAFIAVGWGL PAVIVGISLG STYRVDEPLG YRQEEFCWLA SVDHKQTFST
KKPMFWGFVL PLLIMLILNT AILLHFMYNI CKTNPNLNTN RIEQHHNNQP PPHNRGHNEQ
RRNNQPPPHN SGHNEQRRNN QPPPHNSGHN EQRRNNQPPP HNRDHTEQHH NNQPPPHNRD
HTEQHHNNQP PPHNSGHNEQ RRNNQPPPHN RDHNEQRRNN QPPPRNRDHN EQRRNNQPPP
HNSGHNEQRR NNQPPPHNSD RTESAGMHQA SALCNRSTHL FDPPNILNCS LTLDTIYAWV
SGATVEEKQK LASSTQILTS IPERLTPDNI TNAAQIANAL LSDQRTTDIA VSVVATVSQL
LNASRFNENI GFVLYDNDQF FQSKSFQPSL DTKRRVISAN LEENPEIVQF TVSPSADSTM
SLNDFACVFW SYSENDWITD GCTKTVSSSG SKGCSCKNKR KANFAILMAY DIDYKYSEAL
HWISITGCAL SVLGLCATAL YQIITRKSRG GNPTLLVVTI CLSMTVFYLL FVFGINNPIQ
HRNNDTGVSG ENIVPESDHH KYPDEGPCTA FTALLQYFLL ATFTWNTLYG INVYMHFHDS
VSGTPRWFPK VSMAVGWGLP AVIVGISLGS TYRVDEPLGY RQEEFCWLAS VDHKQRFSIM
KPMFWGFVLP LLIMLISNTA ILLHFLYNIC KTDPNLNTSP LKKKILSSFS LAVILGLSWV
IGYILLITYD KTLKLILSVV FCLLNTTQAN LTMSLDDFAC VSWNYTEKDW TTDGCTKNDS
PSGCASCSCN NRQKANFAIL MAYNMNYKYS EALHWISITG CVLSVLGLCA TASYQIITRK
SRGGNPTLLV VNVCLSMTVF YLLFVFGINN PIPHKNENVT KVSVQNRDLK YDNSNSDTDG
RCTAVTALLQ YFLLATFTWN TLYGINVYML FQSSVSGTPR WFPKVSMAVG WGLPAVIVGI
SLASTYRVDE PLGYRQEEFC WLASVDTEQR FDFKKPIFWG FVLPVLIMLF SSTAILLHFS
YNICKTDPNL NRSRNTPLRK KILSSFTLAV MLGLSWFTGY FLLVTHENKL TIFLSVVFCL
LNTTQANLTM SLDDFACVSW NYTEKDWTTD GCTKNDSPSG CASCSCNNRQ KANFAILMAY
NMNYKYSEAL HWISITGCVL SVLGLCATAS YQIITRKSRG GNPTLLVVNV CLSMTVFYLL
FVFGINNPIP HKNENVTKVS VQNRDLKYDN SNSDTDGRCT AVTALLQYFL LATFTWNTLY
GINVYMLFQS SVSGTPRWFP KVSMAVGWGL PAVIVGISLA STYRVDEPLG YRQEEFCWLA
SVDTEQRFDF KKPIFWGFVL PVLIMLFSST AILLHFSYNI CKTDPNLNRS RNTPLRKKIL
SSFTLAVMLG LSWFTGYFLL VTHENKLTIF LSVVFCLLNT TQVSGATVEE KQNLASSTQI
LTSIPERLTP HDITNAAQIV NALLSDQQTA HTTAYDINYN YSKALHWISI TGCALSVLGL
CATALYQIIT RKSRGGNPTL LVVNICTSMT IFYLLFVSGI NNPVQHVNVA RVFGENIVPE
SDHHKYPDEG PCTAVTALLQ YFLLATFTWN TLYGINVYML FQSSVSGTPR WFPKVSMAVG
WGLPAVIVSI SLGSTYHWKA PLNYRQEEFC WLASVDTKQR FDFKKPMFWG FVLPLLIMLI
SSTTILLHFL YNICKTNPNL NRSRNTPLKK KILSSFTLAV MLGLSWFTGY FLLITREETL
KLILSFVFCL LNTTQVLINL YVKNEVNSDH NEQHYNNQPP QHNSDRTEQH HNNQSPPHNS
DHNEQHYNNQ PPQHNSDRTE QHHNNQFPPH NSDHNEQHHN NQPPQHNSDR TEQHHNNQPP
QHNSDRTEQH HNNQPPPHNS DHNEQHYNNQ PPQHNSDRTE QHHNNQFPPH NSDHNEQHYN
NQPPQHNSDR TEQHHNNQPP PHNSDGTESE YHSISSRYSQ SAPQRKS
//
