ID   A0A498LEI6_LABRO        Unreviewed;      1588 AA.
AC   A0A498LEI6;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=GTPase IMAP family member 8-like protein {ECO:0000313|EMBL:RXN06620.1};
GN   ORFNames=ROHU_035515 {ECO:0000313|EMBL:RXN06620.1};
OS   Labeo rohita (Indian major carp) (Cyprinus rohita).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Labeoninae; Labeonini; Labeo.
OX   NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN06620.1, ECO:0000313|Proteomes:UP000290572};
RN   [1] {ECO:0000313|EMBL:RXN06620.1, ECO:0000313|Proteomes:UP000290572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN06620.1};
RC   TISSUE=Testis {ECO:0000313|EMBL:RXN06620.1};
RA   Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA   Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA   Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA   Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA   Shah T.M., Rai A., Jena J.K.;
RT   "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC       IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RXN06620.1}.
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DR   EMBL; QBIY01013361; RXN06620.1; -; Genomic_DNA.
DR   STRING; 84645.A0A498LEI6; -.
DR   Proteomes; UP000290572; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   CDD; cd01852; AIG1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR   InterPro; IPR006703; G_AIG1.
DR   InterPro; IPR045058; GIMA/IAN/Toc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10903:SF186; GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED; 1.
DR   PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR   Pfam; PF04548; AIG1; 4.
DR   SUPFAM; SSF58100; Bacterial hemolysins; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR   PROSITE; PS51720; G_AIG1; 3.
PE   3: Inferred from homology;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT   DOMAIN          115..312
FT                   /note="AIG1-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51720"
FT   DOMAIN          634..849
FT                   /note="AIG1-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51720"
FT   DOMAIN          1449..1588
FT                   /note="AIG1-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51720"
FT   REGION          353..426
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          439..612
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          909..1119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1169..1191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1588 AA;  191811 MW;  0CABD618D1A046D5 CRC64;
     MRDVELHRRQ ISLVELPALF NTQLSEEEVM RQTHRCVSLC HPGVHVFIII IPDAPLNNED
     RGEMEKIQRI FSSRINKHIM ILINQNSEHQ TEKLNEETQS VIESFGGRHH FIDLNTQVPV
     LMEKLEQMVE ENSGDCFSTE TLMEAQMEKL LKFEEMKKKI HSLETWFQSQ GLFDTELSNE
     EIQREISNCI SMILPGPHVF IIVINLGQRF TQEEKTSVKI IQETFGENSL KYTMVLFTRG
     DDLNNKTIDQ CLGKSGSTLN QLIELCENRF HVFNNKETGD QTQVTDLLQK IDNMVKANGG
     SYYSCKMFRE MERQIQEQQM KILMEKVEQV NREKEELMNK HKKEKKKMKI KIEEERQNHE
     IDRKKREDEF REREEQYKRD IKKQEEQERK IQDKLKRERE EWEKQKQLEK QRREEGEEKW
     RKKEQAMWDE YNQKLKQEEE RMKKIMEDER QKHEKERKKR EKDFREREEQ SQTEIQRERD
     EWEKQMQEAR QKRDEEERIR KIEKETLNDN YEKVKQKNEK MQRKEEDLQL QHEEETERMK
     RMIEEEKKKH DKDRKKIEDE FKEREEQNKR DMKDMEEQKK KIQEELKREQ EEWENQKQQE
     RQREEEEKRH RFNELYTGTL KVQHTNNEDS KSDSECLRIL LFGRTGSGKS ATGNTILRKN
     VFYSEDSTQL VTTSCQKEVG EVDGQSVAVI DTPGLFDTTL TKEQVQEEIM NCISLSAPGP
     HAIIIVLSVG NFIQQEKYTL DTIKMMFGPK AADFCIVLFT RGDELKTDSS FVRFIKGELK
     THKIEEYVEK TKNDELKKLI RNCGNRFLAF NNTDTQDQTQ VSKLINITEE MKKNNQGQYF
     TNEVFKEAAI SIEQRKEMIK ENEKKNKAQV EELKAKYDME IKSMTKGLEK KQRADEEKER
     LIKKFREQEE TLRRESEEKE KSEQKKRETE DQKRSEEEKQ QRAEYDQKIE EMKREIEDQR
     IQYKKQQKER EEEDRKREVK YKQDQEKMKN DHEHIMAELR KDQEEEIKKR DSEEQMRKKQ
     EEKEREEWKR KIKEAENDKE TQEEIKQQQG EWKEEKKRQI KEREREERKR KDKHKEQLRE
     KQEELDKIRK KLETNTAEEK KMIEEEREKH RTEREQKKRE YEEKINEMKR HYEQLERERT
     EEWRRRKEED TERRLEKRKK WEKMMEDLKR EHEEEIKRRE REERERIDRE EKECDEMKQK
     YKEEIKKMKK KHEDEVIKQE EELNDFSKRK EQHIQELKKR FEEFQKQMNE AKSLRKDLEG
     KEIETKSLRK DLETKNNEVK RLERELQDDV LMPQILDLKR KIKNTNKAVT AVTRQFEQVR
     KSVSLLQSRC DSIQPAIRKD RDQISDLKSK VDDITLKIAD IENRSRRSNV RLVGLREGAE
     GEYCFAFLKA NLPKWIPSIA NREIKIERAH RIYSDKPSNR PRTVMFKLLD YTERQAILKL
     DDGNSPSDQE CLRILLFGRT GSGKSATGIT ILWKNGFYSK ESSYLVTTTY TKVIGKANDK
     SVAVIDTPGL FDPSLTKEQV QEEIMKCISR SAPGPHAFII VFNVGKITKE EKDTLEMITK
     IFGPKATEFS IVLYARGDKL KIRLKLKN
//