ID A0A498LFD2_LABRO Unreviewed; 2670 AA.
AC A0A498LFD2;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=FRAS1-related extracellular matrix 2-like protein {ECO:0000313|EMBL:RXN06861.1};
GN ORFNames=ROHU_012142 {ECO:0000313|EMBL:RXN06861.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN06861.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN06861.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN06861.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN06861.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FRAS1 family.
CC {ECO:0000256|ARBA:ARBA00005529}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN06861.1}.
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DR EMBL; QBIY01013357; RXN06861.1; -; Genomic_DNA.
DR STRING; 84645.A0A498LFD2; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR Gene3D; 2.60.40.2030; -; 5.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR003644; Calx_beta.
DR InterPro; IPR039005; CSPG_rpt.
DR InterPro; IPR045658; FRAS1-rel_N.
DR PANTHER; PTHR45739:SF4; FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 2; 1.
DR PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF16184; Cadherin_3; 12.
DR Pfam; PF03160; Calx-beta; 5.
DR Pfam; PF19309; Frem_N; 1.
DR SMART; SM00237; Calx_beta; 5.
DR SUPFAM; SSF141072; CalX-like; 5.
DR PROSITE; PS51854; CSPG; 12.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT REPEAT 264..360
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 383..471
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 492..604
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 629..735
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 756..847
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 873..965
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 994..1096
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1117..1210
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1231..1334
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1355..1447
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1467..1556
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1590..1687
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT DOMAIN 1694..1793
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT DOMAIN 1806..1917
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT DOMAIN 1932..2046
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT DOMAIN 2059..2163
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT DOMAIN 2181..2285
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
SQ SEQUENCE 2670 AA; 297218 MW; 9AA1E8726895DCB8 CRC64;
MIDYRFEGSP TRGVETHGLS YAYTPEVSED AILVANNGIH VPFGRSVYID PINDLVIEVQ
PGDRCTITVL ENDPLSQRPG HVSPKKFPCE FGPNDVRYSH FGSRSPAGDR VKLQLRYDTQ
TETIIIPFML EVEVVFTQLE IVTKNMPLVV DKLRGTSNPI GRKVLDFTYD KDSEQCEVTS
LVASSTLPRY GKIVDETKLE KMMDCDLFLK SNIRYEHTST HKSPNKDYIP MVVELRSKEN
NLLKQEFFHV MIRIKEGEEN TPPRPSFVAM MMMEVDQFVM TALTPDMLAA EDAESNTDDL
IFNITSPLSF EEGYIVSTDD RNLPITSFYQ RDLKDLKIAY KPPSLDSDTE RIFQIEFEVI
DTDGGISDPF AFMIVVKPMN TLAPVVTKNT GQLLYEGQSR SLFTQNNLEV SDEDNLDNVR
ITVVDGLRHG HLAVLGTNRK YFTPADLEVG VVVYQHDGSD TYSDNIIFRM SDGKNDVEFL
FPITIVPTDD EPPIINANTG LILFKNQMVP ISQLMLSAAD IDSEDSTIKF TIKPPFSAIG
EVVVRQSEAP EDPSSWKFNA EDGVYEKVVT EWLQKDITDE KLFYRHTGPH ITETVTDQFV
FKVQDDADPP NRSGENSFII KILPIDDIPP VLFPGTTLQM TVHEYQLTHL NKNVLRYTDM
DSEDRDLKYT ITQPPTDTDE NNPIKFGSIV LTDTPDTDVT EFTQAQINHH KISYSPPDLE
LGITPHVVQF HFTVEDTAGN SANGVFTIFL QPVNNKPPQI TNTGFTVLER GVHVITSAEL
DANDLDTDIK AISFTLSQTP QHGHVQQTFA DLKKGSSFKL MDIADGKVSY IHNGDETTSD
SFKLDVSDGV HVVTITVKVA VKLIDDETPT LSLTKGTFGS RLDVLENGAT EITTSVIQGK
DEDTDDLRLT FIVEEAPTFG EILVSGVSSS RFTQADIISG LVVYAHTSGE IGLASTEDFF
NLTLSDMSDE WTVGGNRVNG VRVHVTILPV DNQTPVVTVG STFTVFEGDK NTIGRHQIRV
EDADTPTEDI LCTIIVQPTS GYVENISPAP GSEKSRSGMA VSAFTIRDVN DGHIHYVQSI
HKGVEPVEDR FTFRCSDGVN FSERQFFPII IIPTNDEKPE IFMRELVVME GMNVIIDTPL
LNGVDADVPA EELTFIITKP PNHGFILNQL TSGSVPITNF TLEQIKEASS IIYEHDDSET
TEDKFDVLLT DGKHSAEATI MIMIIPVDDE TPRLAINDGL EIEIGETKEI NGKILKATDL
DSDDESLTFI IRYGPGQGFL YRKSPGYVEK RSAGSLENIT VGMNFTQNEV NKGLIFYTHN
GQEGIRDLVK FDVTDGINPL IDRYFYITVG SIDMVFPDVI SKGVSLKEGG KVTLTTNLLS
TSDLNSPDEN LVFTITRAPV RGHLESTDTP GMPIVSFTQL QLAGSKIYYI HTADDEVKMD
SFEFEVTDGY NPVFRTFRVS IVDVDNKKPV LTIHDLLVSE GQSKLITPFE LTVEDQDTAE
HLLKFTVTQL PIHGKLLFNN SRQVTSFTKQ DLNENMISYK HDGTESDKDS FSFTVTDGTH
SDFFVFPDTI FETQRPQTMK ITIVSVDNDV PQIVVNKGAP TLKVLTGGHL GYQITSKVLK
AVDRDSNPEA LVFYITAQPE HGYLISLDRG NDSINVFTQA DIDDLKICYI LKDENNATSD
VFSFTVEDNG GNKLKNQQFR LNWAWISLEK PNYVVDEQDK VLEVILRRRG FLGETSFVGI
GTLDGSAERE KDFLGKSQKQ VQFNPGQTTA TWRVRLLSDG KYEQSETFQI ILTEPVMAVL
ESPAIATVEI VDPGDESTVF LPQASFAVEE DIGELLIPVQ RRGDVSEELM VVCHTQQGSA
TGTVPTSVLS YSDYISRPEE QASILRFDKE ETEKHCRVVI IDDSLYEGEE SFNVTLSMPM
GGRLGPEYPT AHIRILPDQD DAPVFYFGNQ EYHVDESDGH VEVRVWRTGT DLSKKATVTV
RSRKTDPVSA EVFFCVHLLA GVDYVGISRN LEFAPGVSMQ TVRVTILDDL GQPVLEGTER
FELILRMPSS GILGNPVKAT IFINDSISDL PKVQFKQAVM TAEESEGHIT AVVLRSGDIR
HKSTVRCYTR QGSAQVVSDF DERPNTDTSV VTFLPGESEK PCLLKLVDDS IHEEEEELRL
VLGSAKSDSP YGASIGNQNE TLIKIKDSTD KPIIKFAETK FSVSEPKESG QMTLVKIPIR
RTGDVSKVSL VRVHTKDGSA VSGEDYHPIS LDVEFKAGEI EHVVEVEILF DGVREMREAF
TVHLKPDENM VAEIQMTKAI VYIEETNSMA DVTFPSLPHV VSLLHYDDIR RTKQNGHPPA
GYPVVCVTAC NPKYPDYDKT GSICISERIN DTLTRYRWLI SAPSGPDGVT SPMREADFDT
FFTSSKMITL DSIYFQAGSR VQCAARAVNS NGDEGLELSS PIVSISMEEG MCQPRKLGTV
GAEPFSAKLR YTGAEDPEYA NLVKLTVTMP HIDGMLPVVS TRALSNFELT LSPDGTRVGN
HRCSNLLDFN EVSTRHGFLT KATRNIESVG ETLPYQYSPV LRGQSTLRFY RNLNLEACLW
EFVSYYDMSE LLTDCGGTIG TDGQVLNLVQ SYVTLRVPLH VSYVFHSPVG AGGWQHFDLH
SELRLTFVYD TAILWRDGVG SPPQAELQGK
//
