ID A0A498LKB8_LABRO Unreviewed; 679 AA.
AC A0A498LKB8;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=CUB and LCCL domain-containing 1-like protein {ECO:0000313|EMBL:RXN07456.1};
GN ORFNames=ROHU_032376 {ECO:0000313|EMBL:RXN07456.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN07456.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN07456.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN07456.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN07456.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN07456.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QBIY01013347; RXN07456.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498LKB8; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032101; P:regulation of response to external stimulus; IEA:UniProt.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00057; FA58C; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.170.130.20; LCCL-like domain; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR004043; LCCL.
DR InterPro; IPR036609; LCCL_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR46806:SF1; DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46806; F5/8 TYPE C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF03815; LCCL; 1.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00231; FA58C; 1.
DR SMART; SM00603; LCCL; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF69848; LCCL domain; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS50022; FA58C_3; 1.
DR PROSITE; PS50820; LCCL; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00059}; Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 47..161
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 180..254
FT /note="LCCL"
FT /evidence="ECO:0000259|PROSITE:PS50820"
FT DOMAIN 242..408
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT REGION 273..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 47..74
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
SQ SEQUENCE 679 AA; 75563 MW; 2E02EE3561203340 CRC64;
MPPMSRNSGV SESVMRIHQR QVAAWLLETQ LSGRKGGVTG AITDDGCGHY VLGQESGVLS
SKNYPGTYPN NSWCEWRIHV PIGHTIVLKF GDLNMEKKGC ETDHLKVLKG SYGMENVFWE
YCGDSMPNTT QVHTDSSELI VRFRSSQHIS GRGFLLSYST ENHKVLDSLW SLSVTVMKYC
PAGCAAVTGD VSGDLSLGYR HTSVLCKAAV HAGVIMDQFG GPITVEERRG LSHYPAVRAN
GIQSIDGSLS ESLFTFVTND CSQQSVLQPV STTTNLSSHN TSSDGTEVEW FPNSTQPGVS
DDLNNKHPKS LQIDLGEKRR ITGILTTGLT IAGFEYFVKN YKIEYRERNR WRTFVQYNNT
DDMIFEGNTD SLHQTRNTFH PSIVARSIRI IPQQWHRIIA MKVQLLGCPY VKPIPVNSSS
PVTQEVRPTQ SIHNDMTKPV ASQADLGCWR QIKQPFARHQ STEFTIKYSS EKDPIQKLDL
VTSAMAAEYQ QPLMLGTDTV SRKGSTFRPM DTEAKDKNIE ASSHYDHLQT GIQYALPLTN
QEPEYATPII ERHAFRKDPF LPDPSYSVPG VVLNKSPSFR AVEGSNCRKV IGGLAGGYQM
PHAKTDRGNY PEDIYDSPKI RKPVVQNGSC SEYQRPQVKS PVRECYSTPR DCVRLPFAGY
RPDPEGSRSD PEGSSSEGS
//
