ID   A0A498LUW7_LABRO        Unreviewed;       726 AA.
AC   A0A498LUW7;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Inner centromere A-like protein {ECO:0000313|EMBL:RXN12249.1};
GN   ORFNames=ROHU_010175 {ECO:0000313|EMBL:RXN12249.1};
OS   Labeo rohita (Indian major carp) (Cyprinus rohita).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Labeoninae; Labeonini; Labeo.
OX   NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN12249.1, ECO:0000313|Proteomes:UP000290572};
RN   [1] {ECO:0000313|EMBL:RXN12249.1, ECO:0000313|Proteomes:UP000290572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN12249.1};
RC   TISSUE=Testis {ECO:0000313|EMBL:RXN12249.1};
RA   Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA   Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA   Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA   Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA   Shah T.M., Rai A., Jena J.K.;
RT   "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC       IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RXN12249.1}.
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DR   EMBL; QBIY01013073; RXN12249.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498LUW7; -.
DR   STRING; 84645.A0A498LUW7; -.
DR   Proteomes; UP000290572; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   CDD; cd01852; AIG1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR006703; G_AIG1.
DR   InterPro; IPR045058; GIMA/IAN/Toc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10903:SF189; GTPASE IMAP FAMILY MEMBER 4-RELATED; 1.
DR   PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR   Pfam; PF04548; AIG1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51720; G_AIG1; 1.
PE   3: Inferred from homology;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT   DOMAIN          226..424
FT                   /note="AIG1-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51720"
FT   REGION          29..98
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          134..160
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          181..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          488..521
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          537..691
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..205
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   726 AA;  89165 MW;  998821CEE6AC2C7F CRC64;
     MEKEMQAKEK KMLLIKHEEE IEKMKTVMKE VKQQSKRSED EFRERAERYK MEIKERQEQE
     RKMREEMERE RKEWEKQKQQ ERQRREEEDE KRREKEQAMW EKYYQTLEQE RERRLKEREE
     LQLKYVEEKG KIKMMMEKER QNHNEERKRK EAEFRERDEQ YKRDIKDIED QERKIRKEMR
     REREEWEKQK QQERQREEEE NKMNELYTGT PEVQHENNDE DSSSAPECLR ILLFGRTGSG
     KSATGNNILG NDEFQNEDSS QLENIVCKKG IGEVDGRSVA VIDTPGLFDT SLENGLVVEE
     IMNCISLSAP GPHVFIIVLS LGSIIQEERD TLDMIKMIFG PKAADFCIVL FTRGDNLKKQ
     TIDQYVEKSK NAELKKLIKE CGERFLVFNN TKKEDRTQVT NLLEMIEEMK KGQYFTNEMF
     EEAGISIEQR MEMIEENKRK NLVQVEELEA KYDMEDQRMR MRLEEKKLKI DEERERLKKL
     FREQEETLRR EFEEKEKSEQ NKRETEDQKR SEEEKQQRAE YDQRIEEIKQ EFENEIIQCE
     KHQDEDRKRE ECKQDQEKMK NEESILAELQ KEGSERQETG REYEEKINEI EGQYEQLQQV
     REEEWKKKKQ EDKERQVEKR QRWEKMMEDL KQEQEEEIKR REREERESIE REEKECDEMK
     QKHAEEIQKM KKIHEEEAKK QQEELNDFEE RKNKHIEEFK GRLEEELNKV NTLKKELKDK
     WSCSVM
//