ID A0A498LWJ1_LABRO Unreviewed; 389 AA.
AC A0A498LWJ1;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Inhibin beta A chain-like protein {ECO:0000313|EMBL:RXN11933.1};
GN ORFNames=ROHU_029802 {ECO:0000313|EMBL:RXN11933.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN11933.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN11933.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN11933.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN11933.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN11933.1}.
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DR EMBL; QBIY01013101; RXN11933.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498LWJ1; -.
DR STRING; 84645.A0A498LWJ1; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19404; TGF_beta_INHBA; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF293; ACTIVIN BETA A SUBUNIT; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 1: Evidence at protein level;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A498LWJ1};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..389
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019751618"
FT DOMAIN 268..389
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 389 AA; 43134 MW; 9D7382EE98845493 CRC64;
MSPLPVLSGI FLLLIQTCSL SAMVTKGSLT TSEQAATDCP SCALARLRKG EDEGAQQDVV
EAVKRHILNM LHLQERPNIT HPVPRAALLN AIRKVHVGRV AKDGSVLIED EASSRLDTEQ
AEQTEIITFA EAGEAPGIVN FLISKEGGEM SLVEQANVWL FLRLPKGNRT RANVTIRLLL
QQGTGEKVLV EKSVDTRRSG WHTFPVSDSV QALLQHGGST LSLRVSCPLC ADARATPVLV
TPGGGEREQS HRPFLMAVVR QMDDLSLRRR RKRGLECDGK VRVCCKRQFY VNFKDIGWND
WIIAPSGYHA NYCEGDCPSH VASITGNSLS FHSTVINHYR MRGYSPFTNI KSCCVPTRLR
AMSMLYYNEE QKIVKKDIQN MIVEECGCS
//
