ID A0A498MDS5_LABRO Unreviewed; 936 AA.
AC A0A498MDS5;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732};
GN ORFNames=ROHU_027970 {ECO:0000313|EMBL:RXN15625.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN15625.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN15625.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN15625.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN15625.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC 2.A.22) family. {ECO:0000256|RuleBase:RU003732}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN15625.1}.
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DR EMBL; QBIY01012838; RXN15625.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498MDS5; -.
DR STRING; 84645.A0A498MDS5; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR CDD; cd11496; SLC6sbd-TauT-like; 1.
DR InterPro; IPR000175; Na/ntran_symport.
DR InterPro; IPR037272; SNS_sf.
DR PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR PANTHER; PTHR11616:SF237; TRANSPORTER; 1.
DR Pfam; PF00209; SNF; 2.
DR PRINTS; PR00176; NANEUSMPORT.
DR SUPFAM; SSF161070; SNF-like; 2.
DR PROSITE; PS00610; NA_NEUROTRAN_SYMP_1; 1.
DR PROSITE; PS00754; NA_NEUROTRAN_SYMP_2; 1.
DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Symport {ECO:0000256|RuleBase:RU003732};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003732};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003732}.
FT TRANSMEM 20..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 507..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 548..570
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 604..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 660..693
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..730
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 742..765
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 785..810
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 831..852
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 872..894
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 936 AA; 106610 MW; 91EA3287753977B4 CRC64;
MKKTKGQIEE RGHWESKTEF ILAVAGIVIG LGNVWRFPYL CYKNGGGAFL IPYLVFVVTC
GVPLFLLETA MGQYTQEGGI TCWRRLCPLA EGVGYAGQLI ILYNCMYYII ILAWALFYLI
YSFSLQLPWD SCDNIWNTDD CVNLASNNLT LNHTVLINST SSVTEFWRNR VLVLSDGIEQ
VGQINWEILL CLIVMWIICY FCVWKGVKST GKVVYFTATF PYVMLVVLLI RGLTLPGALQ
GIMFYLYPEP ARLSDPQVWM EAGAQIFFSY ALGTACLTVL GSYNKYNNNC YRDSLWLCLL
NSSTSVVAGF AVFSVLGFMA QKQGVPIDEV AESGLAFIAY PQAVAMMPLP QLWAVCFFIM
IILLGLDTQF VAMEVFMTSV MDLFPTVLRK AGHREIFLLV FCVFCFFSQL VMVTEGGMYV
FQLFDYYACS GACLLFLCVF ESLAMGWIFG AERMFDVIED MTNSRPNYIF MLCWKYLTPL
VSLVSFVCSL VKYKPLTFNR WYVYPDWAYA LGWLLALSSI LLVPGWARGR LFVEKGSLKQ
ITYFSTGVFP GAFLIPYLVF VFTCGVPLFL LETAMGQYTQ EGAITCWHQL CPLAEGIGYA
GQLILLYNCM YNIILAWALF YLIFSFNFQL PWASCDNTWN TVWIICYFCI WKGVKSTGKV
VYFTATFPYV MLLVLLIRGL TLPGALQGVV FYLYPEPARL YDPQVWMEAG TQIFFSFSVC
FGSLIAQCSY NQYKNNCYRD CLWLCLLNSA TSLVAGFAVF SVLGFMANRQ GVPIEEGGMY
VFQLFDYYAC NGACIFFLSV FESLAMGWIF GAERMFDVIE DMTKSRPNYM FMLCWKYLTP
LVSLVSFVYS LVEYKPLTFN RWYVYPDWAY ALGWLLALSS ILLVPGWALC RMYFGKGNLK
QRWHQLCSPD KNLPLTCKQQ TKIQGTTLTT EVEDTN
//
