ID A0A498MQU2_LABRO Unreviewed; 517 AA.
AC A0A498MQU2;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Inositol polyphosphate 5-phosphatase K-like isoform X2 {ECO:0000313|EMBL:RXN23141.1};
GN ORFNames=ROHU_006448 {ECO:0000313|EMBL:RXN23141.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN23141.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN23141.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN23141.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN23141.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase
CC type II family. {ECO:0000256|ARBA:ARBA00005910}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN23141.1}.
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DR EMBL; QBIY01012567; RXN23141.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498MQU2; -.
DR STRING; 84645.A0A498MQU2; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR CDD; cd09094; INPP5c_INPP5J-like; 1.
DR Gene3D; 2.60.40.2840; -; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR046985; IP5.
DR InterPro; IPR000300; IPPc.
DR InterPro; IPR041611; SKICH.
DR PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR PANTHER; PTHR11200:SF117; INOSITOL POLYPHOSPHATE 5-PHOSPHATASE K; 1.
DR Pfam; PF17751; SKICH; 1.
DR SMART; SM00128; IPPc; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A498MQU2};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT DOMAIN 71..392
FT /note="Inositol polyphosphate-related phosphatase"
FT /evidence="ECO:0000259|SMART:SM00128"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 59480 MW; D988CF8DC8445BDE CRC64;
MADIFDVPRV RSDSTSTTAS QSSSSRQILR QRLAQLLVCL EDLSSDDETN EEVSRTLDEA
FYLCGKYTNR ESFRLHMVTW NVGTAEPPAD VRSLLQLDSQ PATDLFVIGL QEVNATPVRY
ISDLISEDSW SHLLMDTLAP MGYIKVTSVR MQGLLLILFA KQVHLPFIRD IQSTYTRTGL
FGYWGNKGGV SVRFSFYGHM LCFLNCHLAA HMNYALQRMD EFEYILDTQD FDMYNTPQVL
DHKVVFWFGD LNFRIADHGM HFLRSSINNG RFNLLWDRDQ LTMMKKKEPI LQEFEEGPLC
FKPTYKFDRF SETYDTSGKK RKPAWTDRIL WRIKPKAIET EDENMSTTSS TDDDEYPIKV
TQDMYTCDVS YGVSDHKPVI ATFNLEMRKK VETPLVTLTV KGHWSADEDA TFTYTILENF
ESSTWDWIGL YKIGFKSASD YSAFTWVKDD EVAANGEVVT VQMSKNELPL LAGDYVLGYY
STNMQTLLAF SPTFQILESQ QAVMERLVPE NINGHEK
//
