ID A0A498MUL6_LABRO Unreviewed; 2169 AA.
AC A0A498MUL6;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 10.
DE SubName: Full=Inter-alpha-trypsin inhibitor heavy chain H3-like isoform X1 {ECO:0000313|EMBL:RXN23124.1};
GN ORFNames=ROHU_006521 {ECO:0000313|EMBL:RXN23124.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN23124.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN23124.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN23124.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN23124.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN23124.1}.
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DR EMBL; QBIY01012568; RXN23124.1; -; Genomic_DNA.
DR STRING; 84645.A0A498MUL6; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 3.
DR InterPro; IPR013694; VIT.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10338:SF156; INTER-ALPHA (GLOBULIN) INHIBITOR H3-RELATED; 1.
DR PANTHER; PTHR10338; INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER; 1.
DR Pfam; PF08487; VIT; 3.
DR Pfam; PF00092; VWA; 3.
DR SMART; SM00609; VIT; 3.
DR SMART; SM00327; VWA; 3.
DR SUPFAM; SSF53300; vWA-like; 3.
DR PROSITE; PS51468; VIT; 3.
DR PROSITE; PS50234; VWFA; 4.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A498MUL6};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT DOMAIN 1..70
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 224..353
FT /note="VIT"
FT /evidence="ECO:0000259|PROSITE:PS51468"
FT DOMAIN 479..551
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 882..1011
FT /note="VIT"
FT /evidence="ECO:0000259|PROSITE:PS51468"
FT DOMAIN 1137..1209
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 1531..1660
FT /note="VIT"
FT /evidence="ECO:0000259|PROSITE:PS51468"
FT DOMAIN 1786..1858
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 1415..1435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2064..2085
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2169 AA; 244348 MW; DCA8635C8EB8A3CC CRC64;
MQKGETNPVK IQKNVKEAIG GKFPLYSLGF GFDVSFEFLN KLSLENKGVA RRIYEDSDAD
LQLQGFYEEV AIPLLTDVQL NYQGVGNLTQ STFNQYYNGS EIVVAGQITD NSLESFTTEV
IALSKSTKVV YHSNVPTGDL DIPQNKNFIK RLWAFLTVKQ LLEKMVLLEG LEKDNAKKEA
LALSLKYKFV TPLTSLVVTK PQDEEMQIMM DRAALRLILL GVFLISAASD PVGKKENVDI
YSFYINSTVT SRYATTVITS RVANTLNESQ EIQFEVKIPK NAFISKFRMT IEGKTYDGVV
KEKEEAQQQY NQAVSRGQSA GLIKSVGRTL EDFKTSVTVA AFSKVTFELT YEELLKRRLG
KYELLINAQP MQPVADFKMD VHIQEKPGIS FLEVKGDLST GDLANAIKTT RADKDAWVTF
YPTRDQQTKC KSCGENGMNG NLLITYDVER RNPKGEVMVS NGYFVHYFAP SDVPRIPKNV
VFIIDQSGSM HGRKIEQTRL ALLRILSDLD EDDHFGLITF DSEVSLWKRE LLKATETNLE
NAKSFVKEIR DRGGETNIEK IMANVKGAIG TKFPLYCLGF GYDVNFDFLT KMSLENGGVA
RRIYEDSDAD LQLQGFYDEV AVPLLTDIQL KYPGGTNLTK TSFGLYFNGS EIVVSGQITD
NSVESFTTEV IAVSKGSNVM YQDTIMTKDP SDVPPENEDF MQRLWAYLTV QQLLERQVLL
KGQEKEDKKK EALKLSLKYK FVTPLTSMVV TKPQEGDVEV ADKPKEGETP PRPPIMNLRP
IPHGAAAFPG VRVEDHDFGS KLILDQRQMI PWKTIVATAM PVPTVRRNRF VLSVDGQSKP
LCFDVPVPYK LRLLRGLTSR LFPMQIMMDR AALRLILLGV FIISVTSVPI KKKENVDIYS
FYINSTVTSR YTTTVITSRV ANTLNESQEI QFEVKIPKNA FISKFRMTIE GKTYDGVVKE
KEEAQQQYNQ AVSRGQSAGL IKSVGRTLED FKTSVTVAAF SKVTFELTYE ELLKRRLGKY
ELLINAQPMQ PVADFKMDVH IQEKPGISFL EVKGDLSTGD LANAIKTTRA DKDAWVTFYP
TRDQQTKCKS CGENGLNGNL LITYDVERRN PKGEVMVSNG YFVHYFAPSD VPRIPKNVVF
IIDQSGSMHG RKIEQTRLAL LRILSDLDED DHFGLITFDS EVSLWKRELL KATETNLENA
KSFVKEIRDR GSETNIEKIM ANVKEAIGTK FPLYCLGFGY DVNFDFLTKM SLENGGVARR
IYEDSDADLQ LQGFYDEVAV PLLTDIQLKY PGGTNLTKTS FGLYFNGSEI VVSGQITDNS
VESFTTEVIA VSKGSNVMYQ DTIMTKGPSD VPPENEDFMQ RLWAYLTVQQ LLERQVLLKG
QEKEDKKKEA LKLSLKYKFV TPLTSMVVTK PQEGDVEVAD KPKEGETPPR PPIMNLRPIP
HGAAAYYDFG SKLIFDQRQM SGPVRATAMP VSTVRRNRFV LSVDGQSKPL CFDVPVPYKL
RLLRGLTSRL FPVQIMMDRA ALRLILLGVF IISVTSVPIK KKENVDIYSF YINSTVTSRF
ATTVITSRVA NKLNESQEIQ FEVKLPKNAF ISKFRMTIEG KTYDGVVKGK EEAQQQYSRA
VSQGQSAGLI KSVGRTLEDF KTSVTVAAFS KVTFELTYEE LLQRRLGRYE LLINAQPMQP
VADFKLDVHI QEKPGISFLE VKGDLSTDDL ANAIKTTRAD KDAWVTFYPT RDQQTKCKSC
GENGMNGDLL ITYDVERKNP KGEVVVSNGY FVHYFAPSDV PRIAKNVVFV IDRSGSMHGR
KIEQTRLALL RILSDLDEDD HFGLITFDSE VSLWKRELLK ATETNLENAK SFVKEIRDRG
GETNIQKIMA NVKGAIGTKF PLYCLGFGYD VNFDFLTKMS LENSGVARRI YEDSDADLQL
QGFYDEVAVP LLTDIQLKYP GGTNLTKTSF GLYFNGSEIV VSGQITDNSV ESFTTEVIAV
SRGSNVMYQD TIMTKDPSDV PPENEDFMQR LWAYLTVKQL LERQVLLKGQ EQEDAKKEAL
KLSLKYQFVT PLTSMVVTKP QEGEVEVADK PKEGETPPRP PGQMPMVHEE KIFSVDSVST
VRRNRFVLSV DGFSMNGDSM IGRKGFREIA FHYKTNNLAI NTRVIKYHDG PNKVEFLWSQ
EPTQHNTEK
//
