ID A0A498MVU0_LABRO Unreviewed; 459 AA.
AC A0A498MVU0;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 03-MAY-2023, entry version 17.
DE SubName: Full=Friend leukemia integration 1 transcription factor-like isoform X3 {ECO:0000313|EMBL:RXN20917.1};
GN ORFNames=ROHU_024639 {ECO:0000313|EMBL:RXN20917.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN20917.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN20917.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN20917.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN20917.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN20917.1}.
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DR EMBL; QBIY01012628; RXN20917.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498MVU0; -.
DR STRING; 84645.A0A498MVU0; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd08541; SAM_PNT-FLI-1; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR003118; Pointed_dom.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR035573; SAM_PNT-FLI-1.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF161; FRIEND LEUKEMIA INTEGRATION 1 TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00178; Ets; 1.
DR Pfam; PF02198; SAM_PNT; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SMART; SM00251; SAM_PNT; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR PROSITE; PS51433; PNT; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 119..205
FT /note="PNT"
FT /evidence="ECO:0000259|PROSITE:PS51433"
FT DOMAIN 288..368
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 41..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 459 AA; 51653 MW; 1FCE263D4C45B4F3 CRC64;
MFQTVPDTSS YVKEALSVVS EDQSLFEPPY AAAAPLPKTD MTASGAQDYG QPHKINPIPP
QQEWINQPGR VNVKREYDHI NGSSRESPVD CSVGKCNKMV GGTDASQMNY TGYMDEKCAP
PPNMTTNERR VIVPADPSLW SPDHVRQWLD WAIKEYGLQE IDTAMFHNTD GKELCKMSKE
DFLRLTNVYN TEVLLSHLNY LRESSSSISY NTPSHTDQSP RLPAKDDASY DAVRRAGWSN
NMHSGKGSPT VVSQNVSKNT EQARPQPDPY QILGPTSSRL ANPGSGQIQL WQFLLELLSD
SANAGCITWE GTNGEFKMTD PDEVARRWGE RKSKPNMNYD KLSRALRYYY DKNIMTKVHG
KRYAYKFDFH GIAQALQPHP TETTMYKYPT DLPYVPSYHA HQQKVNFVSP HPPSMPVTSS
NFFGPTTPYW SSPTGGIYPN PSVPRHTNSH VPSHLGSYY
//
