ID A0A498N1F1_LABRO Unreviewed; 1804 AA.
AC A0A498N1F1;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 22-FEB-2023, entry version 14.
DE SubName: Full=Coiled-coil domain-containing protein 108 {ECO:0000313|EMBL:RXN28038.1};
GN ORFNames=ROHU_019543 {ECO:0000313|EMBL:RXN28038.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN28038.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN28038.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN28038.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN28038.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN28038.1}.
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DR EMBL; QBIY01011906; RXN28038.1; -; Genomic_DNA.
DR STRING; 84645.A0A498N1F1; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0042470; C:melanosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0032402; P:melanosome transport; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR031638; Melanoregulin.
DR InterPro; IPR008962; PapD-like_sf.
DR PANTHER; PTHR46127; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65; 1.
DR PANTHER; PTHR46127:SF1; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF15812; MREG; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT DOMAIN 150..210
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 152..211
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1407..1457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1627..1668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1408..1441
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1627..1646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1804 AA; 202430 MW; FA933F15A2ED366A CRC64;
MDKSKNFRID ALLSESSQRI VREDSPGLCN DGSDIEPVIC KRTENSPPRG FQLQTGVIPK
PGMLNISHPG LTSLSQGSMP GMYPSPMYSI TALGAQHPTF AYSGFPQPYP EHLKAAAVAG
SFPLEHWLRA GLIMPRLADY SGAPQSGLIG KCRRPRTAFT SQQLLELENQ FKLNKYLSRP
KRFEVATSLM LTETQVKIWF QNRRMKWKRS RKAKEQAAQL ETDGCAMLTD HPVNPLSSGI
PFGVTHNPHR KCEYADTIEF QSKEGSFHVS LRAVIPHHAL EVPDAVMLPP CAAQHSSQTS
FVFRNSSKLQ TEFKWFVDPP FQLSPENGQL KPGEECRVTV EFKPQQALVY QAEACCAFGD
DGENSCTVLL RGLCKYPHLQ ISSSGQEEGC KVLEFGSVAV GDSLERHFEI YNLSTVSTTF
SLSWLRRPAL MDSVFCCEVR EGKIAPNSVL KVPICFSPLT VDSISVDYLS LTCPGAVGKD
LLKVSGTCIG PIVSLNTSVL DFGCVEEGTE VTHNVQIINS SEVLAHYQFD VDTGSHNVFR
IDKPCGSLPG SSKITLCVKF CPHQPIAYLK TVTCLLLHRE PLFLDLIGTC HSEQSKPAVL
NSMHLSIYRM NLLRGLTCYP PDILSALLDE HKLKLDDSGA LLIQEFPEED IDNSTPLFNP
RSLLEEYFHV NSAPEVETEL DDTSNPSKFP TPHVTVQPSE LLFYDGPASK SVSITNHTKG
KICLMWTHGA DSPFSISPLS CELGPLKSTA FRVTYSPNQQ NVFHAAQLEC FSFYKVLRDH
RNVEDRTLCP PWCLTVRASG HSFQPGKEHF IPKFSLQHPK VVFPPLKQVS YRSILLQNTG
DLPLIFRLDP EECPSVCVLP PSGLVPPGSH QILTFRCTPS PDHPAKKLSM SMEGDGNLFF
QPTAVGSCSE RTLRVKNMSR VPVEFKWRLC GSDQRVLTVP PDTDTLQPNE LKVQKWSFAP
IEEMTYNMKP SLTFWPVQMP QCKKSRLTIK AVGLASKGSL QAEHPVIDLG EVLVGSSMLD
FSFSAATLGS DPSSILLLFK NPGSIPVEWS FLLPEDQQIE LEYWAESGDF SPSEFHLMKI
QDHRLFSISP RSGKLLPGQQ RTVQFTYRHD FVGTDRLPVL LKLSHGREIL LNFIGVTVER
DRRYIHLSSN RHIFSPVAIG GFSPPKQVFE LYNGGPLPLR YHIDTTPLEE LMEENFSHPV
LQCLNPGGEV EPGDTALVEW IFSPLEAKTY SVDVPIHVVE GDSMFVTFEG QGFDERESEP
IQIQDGRITV PCTQRIPVPG QVVFLSEERV CFGDIPVGSR STRILFLTNV SHTDQVLYKW
NGASAECQQT VKIHPESGRL APEESVLCIL TIQASGSPAF YQQDLICEIT VVKQLAQYHR
DLRQWKEETE RQKYEFTITE KDLKPTNQLD KCSQTLPPIR SSDQAENGPS VRPSRAEQRA
QQQTGQERRR CPEPPRPAIL HLGVTARSHS LMEYQTHFPT QFKTHYINRS LLDEPQFQQS
LVEGDNEQVP YFTQLRPAPV LPTQTQPGSP AGNQNPVEMS SVTCVTPAET YTRNCSTADR
PKSECDQESL KEVQEEIKVK VQESIRRLPE FYDLVEDILL NTLQNLMTEA FLGELVLTTR
PRIIALPPSS SRTSMSSGSE TAVAHELQDS RSGPEKEGRT WSSTQTSICT TEGESDAELH
AFIKMRNKVD KDTEEWEKLN YDIHTLKYAR KEVCTRWKKI LLQLGYQREA DSLLTVNRQT
ILSDWDNVEK ARELLRLLSE ETGLFPRGLS NSERYVFVMD RLVSLDSAED FVRLAKEKYP
RIES
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