ID A0A498N2P9_LABRO Unreviewed; 513 AA.
AC A0A498N2P9;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Retinoblastoma-associated-like protein {ECO:0000313|EMBL:RXN27041.1};
GN ORFNames=ROHU_020494 {ECO:0000313|EMBL:RXN27041.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN27041.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN27041.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN27041.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN27041.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN27041.1}.
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DR EMBL; QBIY01012082; RXN27041.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498N2P9; -.
DR STRING; 84645.A0A498N2P9; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.472.140; -; 1.
DR Gene3D; 6.10.140.1380; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR002720; RB_A.
DR InterPro; IPR028309; RB_fam.
DR InterPro; IPR024599; RB_N.
DR PANTHER; PTHR13742:SF17; RETINOBLASTOMA-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR13742; RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED; 1.
DR Pfam; PF11934; DUF3452; 1.
DR Pfam; PF01858; RB_A; 2.
DR SMART; SM01367; DUF3452; 1.
DR SMART; SM01368; RB_A; 1.
DR SUPFAM; SSF47954; Cyclin-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT DOMAIN 91..216
FT /note="Retinoblastoma-associated protein N-terminal"
FT /evidence="ECO:0000259|SMART:SM01367"
FT DOMAIN 360..498
FT /note="Retinoblastoma-associated protein A-box"
FT /evidence="ECO:0000259|SMART:SM01368"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..248
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 513 AA; 58260 MW; D82CC2BA9768F883 CRC64;
MPPKKRSSSG TPQKKEFKGN AKNGSPDSSE NAVLSPERHK DKEPEFVSLS EELQATNPIC
DHAWRIWERE IRSMDKANMP YSNRQQWGAC LFIAGMELDG ISLTFTQFLK VVGLNVKQFI
SLVRKMDVNV DTISPKVNAA LKRLENKYEV TLALYQRFVK TCEKISAEPD KAKRTELWES
SWTMFLLAKG TFLQMEDDLV IAFQLLLCVL EFFTKRFTPS LLQSPYKSAV NSSTLSPPTR
SSRRNQGKAN PRPPEMDVQL LETLCKESDC SVDEVKNVYQ TTFCAFLDSV GLSGLQGLPP
METLSKQYEE LYHKNKDFDA RLFLVDDETL SPNKIEVPKV EMTPRKNISG DDVAIPVPQT
PIRAAMNSIQ QLRVDLTSAS DQPSSNLLVY YKNCTVDPSE EIKKRVEELG QVFIKRFAQA
VGQHCEGLGR KRFNLGAQLY YKVMESMLKS LPAFDFYKVI ESFIKAEPTL KHDMMKHLEQ
CEHVIMESLA WKAVSNCLLP FACIVCFIQS PKA
//
