ID   A0A498N2V8_LABRO        Unreviewed;       936 AA.
AC   A0A498N2V8;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Asteroid-like protein {ECO:0000313|EMBL:RXN26503.1};
GN   ORFNames=ROHU_036463 {ECO:0000313|EMBL:RXN26503.1};
OS   Labeo rohita (Indian major carp) (Cyprinus rohita).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Labeoninae; Labeonini; Labeo.
OX   NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN26503.1, ECO:0000313|Proteomes:UP000290572};
RN   [1] {ECO:0000313|EMBL:RXN26503.1, ECO:0000313|Proteomes:UP000290572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN26503.1};
RC   TISSUE=Testis {ECO:0000313|EMBL:RXN26503.1};
RA   Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA   Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA   Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA   Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA   Shah T.M., Rai A., Jena J.K.;
RT   "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the asteroid family.
CC       {ECO:0000256|ARBA:ARBA00007398}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RXN26503.1}.
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DR   EMBL; QBIY01012241; RXN26503.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498N2V8; -.
DR   STRING; 84645.A0A498N2V8; -.
DR   Proteomes; UP000290572; Unassembled WGS sequence.
DR   GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR   CDD; cd18676; PIN_asteroid-like; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR026832; Asteroid.
DR   InterPro; IPR039436; Asteroid_dom.
DR   InterPro; IPR008160; Collagen.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006085; XPG_DNA_repair_N.
DR   PANTHER; PTHR15665; ASTEROID PROTEIN; 1.
DR   PANTHER; PTHR15665:SF1; PROTEIN ASTEROID HOMOLOG 1; 1.
DR   Pfam; PF01391; Collagen; 2.
DR   Pfam; PF12813; XPG_I_2; 1.
DR   Pfam; PF00752; XPG_N; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT   DOMAIN          1..97
FT                   /note="XPG N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00752"
FT   DOMAIN          128..180
FT                   /note="Asteroid"
FT                   /evidence="ECO:0000259|Pfam:PF12813"
FT   REGION          393..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          552..577
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          658..750
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        394..417
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        731..747
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   936 AA;  102093 MW;  821E8A95B5C12106 CRC64;
     MGVHGLTSFV EGNRQFFTDM RLRDCRLVID GCSLYYRLYF NSGLDQARGG DYDTFAVLIR
     QFFAALTECA VQPFVVLDGG MDQTDKKFKT LQERAQSKIR EANTLSRGFH GFVLPLLVCE
     VFKQVLSELG VPFVQCISEA DFEIASLAKH WGCPVLTNDS DFYIFDLKGG YLPFSFFQWN
     NVCGKATERY VPACHFSVNR FCSHFNHINK QLLPLFAVVL GNDYTPGKIT EIFFSRVELE
     RVPSGRKSGR SGSPRIEGFL LWLSQFTNPV VALEEVLEIL GEQRKGNLRA QISAGMRDYQ
     LPQSSSLAQY FSSPQPALPD AQGLPAALVS QPEWLLRMFA SGKLPSLVLD VLVHQKVLLL
     AQVENSNLPS SHTTSLSIRK TIYSLLLEKA RHDSQTPQAV TQRGRGRGRQ SQGKGGQQCD
     VPCVDEYDRQ NLILKKNTVE AQRPKSVPQL ELAAIDKDVA VLRLTDALFI YLFIYLTEWF
     LSRILSDRDP NDVLKRFDPC CLLSPPPPPL FPPPPGVWKR EPTMAIRVGG TRVREEDEKQ
     VKELCCVAGP PGPPGPVGPQ GPSGIPGMEG PKGDKGDIGR PGSKAGCILQ SSTLFMTRTL
     GACNSFTGCQ AMCCPLAVFI GCSPLQVVLG VRVCLGNQVL QGYPAQRDLR WGEKGDPGLM
     GMPGLRGPPG PKGLSGYKGE KGANGLPGML GQKGEMGPKG ELGVPGKRGP TGRPGKRGKQ
     GSDGERGFPG PVGPIGPPGP RGHPGPPGIP ASGLFVVGEK GEKGLPGPPG VCDCSFPSLS
     PASAPLQHRN KYDKVPAIFV VSSEEELKGL HEDNALAFRK DQRSLYFKDK NGWEPIQLMP
     LQATERMRDG NGFCGDGKVQ ELNGEECDDG NKVVTDDCVG CKKAYCGDGY RNEGVEECDG
     KDFGYQTCKS YLPGTFGQLR CTDSCFIDST GCKYRT
//