ID A0A498N4E5_LABRO Unreviewed; 1238 AA.
AC A0A498N4E5;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Ankyrin repeat and SOCS box 2-like isoform X1 {ECO:0000313|EMBL:RXN26564.1};
GN ORFNames=ROHU_020610 {ECO:0000313|EMBL:RXN26564.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN26564.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN26564.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN26564.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN26564.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN26564.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QBIY01012231; RXN26564.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498N4E5; -.
DR STRING; 84645.A0A498N4E5; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 6.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24123:SF140; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR24123; ANKYRIN REPEAT-CONTAINING; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 6.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 22.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 4.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 17.
DR PROSITE; PS50088; ANK_REPEAT; 17.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 189..221
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 222..248
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 255..287
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 321..353
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 354..386
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 386..418
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 428..456
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 458..490
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 772..804
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 805..833
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 838..870
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 871..903
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 904..936
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 937..969
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 969..1001
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1011..1043
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1041..1070
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1193..1235
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT REGION 52..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1238 AA; 137118 MW; F49379AA3AAF692D CRC64;
MAAASVTMAA SGTTTDDLED FSAYAHLSQE QLLQIAIERS LADANLTPWQ NRQLQSHTQA
AATKATQQLP CNPNSANPPS EMKCAKIDRN VHNHIFSNNQ EKVIAWTRHN GHLRVTVETV
NNLDPFLSAI WRGDAKALLD IIHLKSKNLD EPNKDGWLPL HESAYYGHFE CLKILLKAKP
DAINKRTNRS QTPLILAVSR KHVSCVKHLL EEGADPNLAN SQWETPLYKA CEKANEETVE
LLLRFGASPT RACVQGGTPL HEAVRNKKLD ICKMLIHAGA KQWARNVYGI DALFTAAQCN
AVKELNYLIC KGGNVNTQAG DDASALFEAS KNGHAEVVEI LLSKRADVNK ANKTGLLPIH
VAAKNGHDSI VAMLIPRTNV VKVRRSGISP LHFAAERNRD DVLETLIEGG YDINFKLSDD
WSKMYEDRRS TALYSAVANR NTEAAAMLLE AGADPNLDIF NPLLVAVRKG SMEMVSLLVK
HGANVNALLP THPTSFPAAL VFCMRYKAMM KYLLDNGCDA LSCFTCQYGS NPHPPIKLAR
NGRETMYFLN DEPSEYCVEF CEVISAPSVS SWVGPIIDTL LDYVGHVKLC SRIIEHLDSN
KDWAHIKERS GSIMATARVS MPGTTDTNLE FADYSLYSNL SDEELMQLAI ERSIADAQNS
GSGITENSKT AVALNRPAAS RRAPPSQRPQ QQPERAACPA NPPREIEPIA KAISEGDVGS
VRLMVKQPEC NLLKPNKDGW IPLHEAAYYG QDQCIKILLR AQPGMINHRT LKEQTALMIA
VTREHLACVQ CLLEKGADPD IPNKERETPL YKACEKENPA IVAMLLNHGA SVNKNCIQGW
TALHESVCRN NVEICEMLVK AGAKVSMPNM YGITPIFVAA QSGKVDSLRM LLKNGADLNS
QAADGATALY EASKNGHEDI VEFLLSQNAD ANKPGKTGLL PIHIAAQRGN DSIVSMLIPA
TSKARVRRTG ISPLHLAAER NRNDILEVLI EAGFDVNATL SEDRSMMYED RRSTALYFAV
MNNNIEATTM LLETGANPNL DTFNPLLVAL RHGCIQTVTL LVEHGANVSA YIPTHPTTFP
ATVMFCMKYL TILKYLMDNG CDALSCFNCV YGSNPHPPIK TRRNPRYDPD EAVEKTCVQF
CEVISTENYS RWAGPIIDVL LDYVGHVKLC ARLIEHLDSY HEWQSIKEKA MPPRPLMQLC
RLKIRKLLGI KRLKKIHKLP VPPRLIKFLN HQEREQDF
//
