ID A0A498N4J7_LABRO Unreviewed; 814 AA.
AC A0A498N4J7;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Putative serine threonine-kinase irlB {ECO:0000313|EMBL:RXN23805.1};
GN ORFNames=ROHU_022633 {ECO:0000313|EMBL:RXN23805.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN23805.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN23805.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN23805.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN23805.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN23805.1}.
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DR EMBL; QBIY01012558; RXN23805.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498N4J7; -.
DR STRING; 84645.A0A498N4J7; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:InterPro.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1440.180; KEN domain; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR InterPro; IPR045133; IRE1/2-like.
DR InterPro; IPR010513; KEN_dom.
DR InterPro; IPR038357; KEN_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR13954:SF28; -; 1.
DR PANTHER; PTHR13954; IRE1-RELATED; 1.
DR Pfam; PF00069; Pkinase; 2.
DR Pfam; PF06479; Ribonuc_2-5A; 2.
DR SMART; SM00220; S_TKc; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 2.
DR PROSITE; PS51392; KEN; 2.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 2.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|EMBL:RXN23805.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Transferase {ECO:0000313|EMBL:RXN23805.1}.
FT DOMAIN 1..226
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 229..366
FT /note="KEN"
FT /evidence="ECO:0000259|PROSITE:PS51392"
FT DOMAIN 433..689
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 692..814
FT /note="KEN"
FT /evidence="ECO:0000259|PROSITE:PS51392"
FT REGION 309..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 360..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..376
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 814 AA; 94290 MW; 25237E6792D518BF CRC64;
MDRFNYQDLK NEEEFLRLPE LDSPSIVRYV DFAEDDNFGY LVLQLCEYTL EEYIQDHLPD
DTAERTLVLK KLVKEVLCSL QVLHDQKTKV LHRDIKPQNV LIDIKGKARL ADFGISRRLK
QGETTIRTSI AGTRCWKAKE NIHEKVNTGY KRSSDIQVAG MLVYYILSGG HHPFGEDVDC
EYNILRGRYS LQHLDDDVAK DLVEWMIKEN PNERPTVEQT LAHPFFWADD RRVRYLKILG
NEKEAENCRN ADEELLNAFS KHTEGKSFSE WKNKLPSELV QKLDGKKKPY PENTLGLLRF
IRNLHEHYRS APSSDQTSQG NKIPSPPSGP TLSRNQLWFP ELMQLLSGAL CLIPLRKDHQ
EVGSQESERQ DKEVTAGTSV EESISSVQLL TLENPNISRR WHQTSHRWRP KLEKLANIDA
SRTHRLPGLT LVIDSEFLIA NGSDGTQVFL GLRDDGTEVA VKRMIRFNYQ VLRNEEEFLR
LPELDSPSIV RYVDFAEDDN FGYLVLQLCE YTLEEYIQDH LPDDSAERTL VLKKLVKEVL
CSLEVLHSQQ SRVVHRDIKP QNVLIDIKGK ARLADFGISR RFKQTETTLR TRIAGTRCWK
AKETIKEKVN TNYKRSSDIQ VAGMLVYYIL SGGHHPFGED VDCEYNISRG RYSLQHLDDD
VAKDLVEWMI NENPNERPTV EQTLAHPFFW TDDRRVWYLK ILGSEKEAEN CRNADEELLN
VISKHTEGKS YSEWKTKFPS ELVQKLDGKK KVYPENTLGL LRFIRNLHEH YKPDAVKINL
MALFPDLFGT VYILAKERGW NSRESVIMDI NSAS
//
