ID A0A498N6K4_LABRO Unreviewed; 747 AA.
AC A0A498N6K4;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 22-FEB-2023, entry version 14.
DE SubName: Full=Transcription initiation factor TFIID subunit 4-like isoform X2 {ECO:0000313|EMBL:RXN24267.1};
GN ORFNames=ROHU_006186 {ECO:0000313|EMBL:RXN24267.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN24267.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN24267.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN24267.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN24267.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF4 family.
CC {ECO:0000256|ARBA:ARBA00006178}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN24267.1}.
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DR EMBL; QBIY01012545; RXN24267.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498N6K4; -.
DR STRING; 84645.A0A498N6K4; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd08045; TAF4; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR045144; TAF4.
DR InterPro; IPR007900; TAF4_C.
DR InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR InterPro; IPR003894; TAFH_NHR1.
DR PANTHER; PTHR15138:SF22; TAFH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15138; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4; 1.
DR Pfam; PF05236; TAF4; 1.
DR Pfam; PF07531; TAFH; 1.
DR SMART; SM00549; TAFH; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR SUPFAM; SSF158553; TAFH domain-like; 1.
DR PROSITE; PS51119; TAFH; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:RXN24267.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|EMBL:RXN24267.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 427..524
FT /note="TAFH"
FT /evidence="ECO:0000259|PROSITE:PS51119"
FT REGION 27..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 726..747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..113
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 747 AA; 78742 MW; C688055789F07516 CRC64;
MAGASDPLED MLFSEVDEKA VSDLVGSLES QLVGQSEPPA AQPENARPGS AKQQQQQQAG
GTAQLPAPVD SPSEPQQQAQ QQQNARKAAR NPDSDPKDVS LDKHAKALEK ESPLKSHGGS
IIIITTAAAA AASDAPAPGN KGESPRDTRK KHPGNTRTLR SAASHSLNGN GGGAASASPG
TSSPSGTTFT VSSNPQAIAL DRGTPTIALH RLPRHIIASI AQNGNGTSVS ALVQQGARIA
ATGAQVNHSK PPADASGNNA KPQATSAPPA AAATAPVKPA VSVSAAPVIR PAQTQPPAQQ
RVVTPQLIVR PPQQQTTIQL PPGFTIPPGM VLVRTEMGQL VMVPQQALAQ AQAQNSISPR
PSTPTSVATF RVTTPQKAPV AAAVAVTAPQ QVQPALGPQG PLTQMPLAPQ SAAAPAPGAS
VVSQEMQENV KKCKNFLATL IKLASHNSPS PETSRNVKAL VQDLLDAKID PEEFTSRLQS
ELKSSPQPYL VPFLKGIKRA AGPGSQIRMP VVITQTVRAT GTLGKPVAIQ TGKSPAGVTI
QLSGNQKNKL NDPGGGSFRD DDDINDVASM AGVNLNEESA RILATNSDLV GTQIRSCKDE
AFLPTGLLHR RILETAKRFG VTDVPLEAVN FISHATQSRL RTVLEKVSSI AQHRMDSCKE
DEWYEQSSDV RSQLKFFEQL ERMEKQRKDE REREILLRAA KMQQQELAQM RQRDANLTAL
AAIGPRKKRK VDSPGATTTG TEGVFLK
//
