ID A0A498N7L7_LABRO Unreviewed; 1287 AA.
AC A0A498N7L7;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Leukocyte elastase inhibitor-like isoform X1 {ECO:0000313|EMBL:RXN26576.1};
GN ORFNames=ROHU_020622 {ECO:0000313|EMBL:RXN26576.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN26576.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN26576.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN26576.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN26576.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the serpin family. Ov-serpin subfamily.
CC {ECO:0000256|ARBA:ARBA00006426}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN26576.1}.
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DR EMBL; QBIY01012231; RXN26576.1; -; Genomic_DNA.
DR STRING; 84645.A0A498N7L7; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 3.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 5.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461:SF180; LEUKOCYTE ELASTASE INHIBITOR; 1.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR Pfam; PF00079; Serpin; 5.
DR SMART; SM00093; SERPIN; 4.
DR SUPFAM; SSF56574; Serpins; 5.
DR PROSITE; PS00284; SERPIN; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A498N7L7};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT DOMAIN 13..374
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
FT DOMAIN 397..625
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
FT DOMAIN 626..916
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
FT DOMAIN 919..1286
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 1287 AA; 148099 MW; 83CA48F9E8AF7A8E CRC64;
MEDLSRANSL FALDLYRRLS ASNAEENVFF SPLSISTALS MVYLGVRGDT AKEMAKVLSL
SSVSDVHSHF KTLTSTINRP STSYILRLAN RLFGEKTLNF LPEYLHSILK LYHTELQALD
FIGAPEMSRQ LINKWVEEQT ENKIKDLLKR GAVNETTQLV LVNAIYFKGC WIQTFDTRDT
QEMPFKINQN ESRPVKMMYQ KDIFPFRYIP EYELQVLELP YKKFKLSMLI LLPKKTQDDS
DSLLKLESEL TIDKLLDWTK RDNMVPRMEV KVHLPKFKLE FESYLLKILQ EMAVSSVMEG
LFCANGLFAL DLYRALSASN AEKNMFLSIS AALSMIYLGA RGDTAKEMAK VLSFSSVSDV
HSHFKTLTST INRPSASYIL KLANRLFGEK TFSLFALDLY RALSANNAEE NVFFSPLSIS
AALSMVYLGA RGDTAKEMAK VLSFSSVSDV HSHFKTLTST INRPSATYIL KLANRLYGEK
TFNFLPEYLD SILKLYHTEL QAVDFIGASE MSRQLINKWV EEQTENKIKD LLKRGAVNET
TQLVLVNAIY FKGTWMDTFD PKDTHEMPFK INQNESRPVK MMYQKKMFPF RYIPEYELQV
LELPYKKFEL SMLILLPKKT QDDSDSLLKV LFFSSVSDVH SHFETLTSNI NRPSATYNLK
LANRLYGEKT FSFLPEYLVS TLKLYHTELQ AVDFIRAFDE SRQLINKWVE EQTENKIKDL
LKPGVVNELT RLALVNAIYF KGTWMHKFET RNTKEMPFKI NQQNESRPVQ MMFEQKKFPF
RCIQEHKLQV LELPYVNEEL SMLILLPNET QDGSDPLLKL ESELTLDKLL DWTRRDKMAT
WMTIRVHLPK FKLEVESSLS EILQEMGMSS VFQETKADLT GMSSNGRLFI SAVVHKAFIE
QCLSSVMEDL SRANSLFALD LYRALSASNA EKNMFFSPLS ISTALSMVYL GARGDTATEM
AKVLSISSIS DVHSHFKTLT STINRPSATY ILKLANRLYG EKTFSFLPEY LNSTLKLYHA
DLQTVDFIGA SEESRKLINK WVEEQTENKI KDLLKRGIVT DLTRLVLVNA IYFKGTWMHR
FETRDTEEMP FKINQNERRP VQMMYQKEMF PFRYIPEHEL QVLELPYKQE ELSMLILLPN
ETQDGSDPLL KLESELTLDK LLDWTEREKM GTSMDISVHL PKFKLEVDSS LSEILQEMGM
SSVFQETKAD LTGMSTQRRL LISAVAHKAF IEVNEEGTEA AAATAVMVEL DCAFPCQSFI
ADHPFMFFIR HNPTNSILFL GRFRGPL
//
