ID A0A498NEX3_LABRO Unreviewed; 770 AA.
AC A0A498NEX3;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Bifunctional E2 E3 enzyme {ECO:0000313|EMBL:RXN29067.1};
GN ORFNames=ROHU_018796 {ECO:0000313|EMBL:RXN29067.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN29067.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN29067.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN29067.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN29067.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN29067.1}.
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DR EMBL; QBIY01011822; RXN29067.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498NEX3; -.
DR STRING; 84645.A0A498NEX3; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd16655; RING-Ubox_WDSUB1-like; 1.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR000608; UBQ-conjugat_E2.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR46573; WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46573:SF1; WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF04564; U-box; 1.
DR Pfam; PF00179; UQ_con; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00212; UBCc; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51698; U_BOX; 1.
DR PROSITE; PS50127; UBC_2; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A498NEX3};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT DOMAIN 614..770
FT /note="UBC core"
FT /evidence="ECO:0000259|PROSITE:PS50127"
FT DOMAIN 694..767
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REGION 733..770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..770
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 770 AA; 88452 MW; 6EACDCFBFA67F275 CRC64;
MREILDAVFG LLIAPEPSDP LDREVTADQL LATFGVRPYP LWMDKIFKLL QKFRLDKYYK
KFIDLGIKEE LDFFDSVNDM TLKSMDFSQA ERNRYDNMIG YLQRIGSAPV PEGMPVTKSL
NSFHISYRFP KCPGIQEITG LDPAQNTVED LMLRICHENK VDRNMSVCLY TADGMPLTDD
PFFNTWSLND RHIASGSELY AIFTRRENLT ELPPTQRQAN IRNEGPSVIR CHIMLQGDFE
IKVDFESDTL RDVTQRLSLE SSIPAPVLHI RGEEYNHVDK LSELGITEDS VLQFYLSSYD
NEKPSPSLLF QTDVRPFISV HTGILVDTIK EKLKHCGDDF KKVVAYIRRL SGCNALAQSL
FQMICRNFHV TRNQKNESDD LEYYATISLK TYPTGQRLSE PVRVPGTPEV FDRSYILEKI
TDNLGVYLNK DKGDPFKIRI YDCLSGKETT KNVNDLAKIL NDTRTDNTVE VSKTPKEAIV
VLFDSSSSMM EECYDTVSQM KRIDAVKQIF DSFSNRSMSY DFQHVICLVM FNDKVKTLLK
FTENLEAFKE QVHAIEASGY TRLYDALVRG IAELDNIKKR FPACRCRILC LTDGNDFSVL
KKKIRESKSG RFMEKEKRII EELKSLHCDP HPFCSVYPSE TDFTFWRIVM KGPPDTPYEN
GTFELYCQFG DDYPVKPPVV RFYTPQYIGE SNVKVPPHLV CPLTGKIFID PVKAKSGCVY
ERRAIEEYLK TNKNDPVTGK PLSGTDLTPD KNMKKSVMEY RTSQIEETDP
//
