ID A0A498NFS2_LABRO Unreviewed; 1871 AA.
AC A0A498NFS2;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Neural cell adhesion molecule L1 isoform X1 {ECO:0000313|EMBL:RXN30664.1};
GN ORFNames=ROHU_017570 {ECO:0000313|EMBL:RXN30664.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN30664.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN30664.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN30664.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN30664.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC L1/neurofascin/NgCAM family. {ECO:0000256|ARBA:ARBA00008588}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN30664.1}.
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DR EMBL; QBIY01011554; RXN30664.1; -; Genomic_DNA.
DR STRING; 84645.A0A498NFS2; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR026966; Neurofascin/L1/NrCAM_C.
DR PANTHER; PTHR44170:SF51; NEURAL CELL ADHESION MOLECULE L1-LIKE PROTEIN ISOFORM X1; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF13882; Bravo_FIGEY; 1.
DR Pfam; PF00041; fn3; 4.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1871
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019834050"
FT DOMAIN 26..126
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 127..214
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 240..328
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 331..460
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 469..559
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 566..661
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 666..759
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 764..866
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 881..978
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1035..1065
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1511..1546
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1871 AA; 213879 MW; F5DDB1E68DACFA23 CRC64;
MRGLRSLIVG LLSATFSTAF GLYFPPHVEQ LPTITAQTSG SLIALPYDEN FLFKCEAKGN
PRPTYRWTKD GMDFDPRKDP RLIKDESSGT FVIPNIRDKV KYQGKYRCYA SNKLGTAISE
ESEFIVPMVP KFPKEKIEPV VVTVGDSVVL ECNPPQGIPP WQLYWMTKDL RHIEQNERVS
MGLNGNLYFS NTVELDSHDD YCCFASFSKI RTIVQKPSMV LRVKPSQGDD NTMSVQKRKP
SILVPSSHST TYLKKGEELE LECIAEGLPT PEVEWIKMWD NLPKRTQIKN YGKLLTIPNI
TNQDEGKYMC KAKNDLGEAV HHFQVVVEEP PRWQEEPVKS QLAEIGSDIH IKCSATGKPQ
PTITWKRNGH PLDDHPPLIL TRNYLDYATM LGRSVIMDCK VFSSPPATIN WRREDPEGSL
DGERYSLLKN GSLQIHKVEM EDMGQYECLA NNSEGTASLT TELFIKDSTR IVEPPQDMKV
KRGSMAELEC QVECDPTLRR ELKILWMKDG MHILSNVSEG YFTDDGILQI INVSHSDQGN
YTCVVRTSLD QDTASAYVTV LDVPDPPVEL TLSDRKDRSV RLHWAAASDH NSPITEFIIQ
YEENHWEPEK WKELLRVAGS QFSAPVTLYG HINYQFRVIA VNAIGESHPS MPSDRYKTPP
CAPDRNPENI KIEGHLPHQM DISWEPLLPV EHNGPGLEYK LSYRLLGVED SWKEQMVKRH
SFVVRDTPTF VPYEVKIQAF NRHGWAPEPK VVTGYSGEDM PLAAPEDVFV EVLNFTLLRV
SWSPVPQTTL RGHLGGYTVH WWQTQSLLTS KRMPSERQSL TIPGNRSHTM VPGLKPFSEY
SLTVNVFNRR GNGPSSSPIS FTTPQGGKNT LTVDILKFSV PEQPPILKAT NFQKDSITLV
WAPPHETNGF LTGYLLQYQT FNETLGKLNS VNISAPDTTQ WVLRDLQEDN WYKFYLSACT
QVGCGSAISE EGGTVSEAYE LSTSEVTSSE LMSSKQLVAS QKWFVVMLCV VALLTLLALI
GCFVLKNKGG KYAVKEKEHT KADPESHTRG EESPYEYSDN DEKPLKSSQQ LFRDIKEDDS
SEDSSVMSEE DDCEFNEDGS FIGEYSGYKR RVSTEGPLRT IYSRTQTFKQ LFQYIEPKKP
GLPPCLEHDI FEGVLSYDVA LYLKYFIKKK QWLTYSVLNR RIKQFKYKGT DALTKPCAVN
SKQDVYKRQD IDWVDTFLIP WDKFPEELMQ FLEREKRPSP EQRAAIQDTY GCVNWDVKFL
PLEETPESQQ EKKEKLKMMS RNNDANLEEV KSLMKLTFYT QRKQVNQGEN IKYLLEEWPF
WFNELGMAVH FKELTGIGLK ETFTRNLEVK GKRLLNYFSS VGVNKNKKFM EAVTKCKVMR
EQASSCSEDV KEMLLLLLSY FNEKEDAMFH YVEDTCLAEE VDMDKVNLTP TLVACEMTDL
ETTFLRTAIT EVLPDLPEVT KDILEETLQS LGVETYDDFQ FIEESDLLSA LRPIQARKVL
AAWKRKCQTP ETSSSSVSAS PVPPATLRHS SPGSSQSSSS SSSKSPDIDW VDTFLIPWDK
FPEELMQFLE REKRPSPEQR AAIQDTYGCV NWDVKFLPLE ETPESQQEKK EKLKMMSRNN
DANLEEVKSL MKLTFYTQRK QVNQGENIKY LLEEWPFWFN ELGMAVHFKE LTGIGLKETF
TRNLEVKGKR LLNYFSSVGV NKNKKFMEAV TKCKVMREQA SSCSEDVKEM LLLLLSYFNE
KEDAMFHYVE DTCLAEEVDM DKVNLTPTLV ACGGSCFTAK RFMLCVDRNV VHDNIPSFIS
AICMMFGSYY CFNIHYPSEL ASTLEFLQRC FFAINPEKGT KVEKTNTVRL HVNPRVLTLI
QDLSDHEWCD V
//
