ID A0A498NJ66_LABRO Unreviewed; 984 AA.
AC A0A498NJ66;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=Transport Sec24D-like protein {ECO:0000313|EMBL:RXN31846.1};
GN ORFNames=ROHU_016722 {ECO:0000313|EMBL:RXN31846.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN31846.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN31846.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN31846.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN31846.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Cytoplasmic vesicle, COPII-coated
CC vesicle membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC {ECO:0000256|ARBA:ARBA00008334}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN31846.1}.
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DR EMBL; QBIY01011439; RXN31846.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498NJ66; -.
DR STRING; 84645.A0A498NJ66; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd01479; Sec24-like; 1.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 2.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR041742; Sec24-like_trunk_dom.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR006895; Znf_Sec23_Sec24.
DR PANTHER; PTHR13803:SF6; PROTEIN TRANSPORT PROTEIN SEC24D; 1.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR Pfam; PF04810; zf-Sec23_Sec24; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 2.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 1: Evidence at protein level;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A498NJ66};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 342..380
FT /note="Zinc finger Sec23/Sec24-type"
FT /evidence="ECO:0000259|Pfam:PF04810"
FT DOMAIN 419..663
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 668..752
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 764..863
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT DOMAIN 884..938
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT REGION 1..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..158
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..194
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 984 AA; 107217 MW; 5C6C67F5DC69522F CRC64;
MGGYSTGFGN PPPQSHYGYG SPPQGYSAPQ TGVLKPPASS PSGMPPPPVS SQYGANIQQN
GAHPHSFPPP VASAASMSPY GQPPQGAFHS MAQAPPPTQQ LTNQMSAMNI GGYGQRPMQG
PQSPSSSAAP QQFQTSPPPA MGHPPLSPPG PQPSSLGSPP PMATMGSMTA PPMGMSGPPG
PGVHQPPLGP QGYPQQPGSP IAGPYGAQMA GPQMAGPQSG AFPGGFPGGP AQMAGPPQKK
LDPDSIPSTT QVIEDDQAKR GGQVYVTNIR GQVPPLVTTD FTVQDQGNAS PRFMRCTTYS
FPCTADLAKQ CKVPLAAIIK PFATVPKNET PLYIVNHGEA GPIRCNRCKA YMCPYMQFID
GGRRYQCGFC SCVNEVPVQY FQHLDHMGRR MDMYERPELS LGSYEFIATL DYCKNNKPPN
PPAYIFMIDV SFNNIKSGLV KLICEELKTL LDRLPKEEGA ETSAIKVGFV TYNKILHFYN
VKSALAQPQM MVVSDVAEMF VPLLDGFLVN FQESRAVINN LLDQIPDMFA DTNESETVFA
PVIQAGVEAL KAAECSGKLF IFHSSIPTAE APGKLKNRDD RKLVGTEKEK TLFQPQRGVY
EQLTKDCVAQ GCCVDLFLFP NQYVDIATMG DVSSHTGGSI YKYSNFQMEV NGQQFISDLR
KDVEKSIGFD AIMRVRTGTG FRATDFFGAI YMNNTTDVEM AAVDCNKAVT VEFKHDDTLS
EESGAVMQCA LLYTTIGGQR RLRIHNLSLN CSSQLSELYK SCETDALINF FAKSAYRAML
NQPLKMVREI LINQTAHMLA CYRKNCASPS AASQLILPDA MKVFPVYMNS LLKTPALVGS
TELSTDDRAF HRFLVNSMGV EETQVLLYPR LIPLHSMDVS SEVIPAPVRC SEERLNESGM
FLLENGFSMF LWLGQACPPD LIQNLFNVPS LGHLSSEGLL IVKQKDRSDM LFRQHLVEDK
GLHGGASYMD FLCYVHREIR QLLT
//
