ID A0A498NS77_LABRO Unreviewed; 625 AA.
AC A0A498NS77;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 03-MAY-2023, entry version 15.
DE SubName: Full=Rhophilin-1 isoform X1 {ECO:0000313|EMBL:RXN34940.1};
GN ORFNames=ROHU_014583 {ECO:0000313|EMBL:RXN34940.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN34940.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN34940.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN34940.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN34940.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RHPN family.
CC {ECO:0000256|ARBA:ARBA00010369}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN34940.1}.
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DR EMBL; QBIY01011161; RXN34940.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498NS77; -.
DR STRING; 84645.A0A498NS77; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00136; PDZ; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.25.40.280; alix/aip1 like domains; 2.
DR Gene3D; 1.10.287.160; HR1 repeat; 1.
DR InterPro; IPR004328; BRO1_dom.
DR InterPro; IPR038499; BRO1_sf.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR047138; RHPN1_2.
DR PANTHER; PTHR23031; RHOPHILIN; 1.
DR PANTHER; PTHR23031:SF6; RHOPHILIN-1; 1.
DR Pfam; PF03097; BRO1; 1.
DR Pfam; PF02185; HR1; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM01041; BRO1; 1.
DR SMART; SM00742; Hr1; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF46585; HR1 repeat; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51180; BRO1; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS51860; REM_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT DOMAIN 21..95
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 106..465
FT /note="BRO1"
FT /evidence="ECO:0000259|PROSITE:PS51180"
FT DOMAIN 478..542
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 72..99
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 70577 MW; DFBB56DA3647471B CRC64;
MSDSGSDEDR GSTESVRKGC DPLVSTQRSK LQQRRAKLNQ QINRELRLRS GAENLYRASS
NQKVKETVAL ELSFVNSNLQ LLKEELEELN SSMNVYQTES ETVSVPMIPL GLKETKEIDM
TAPLQDFISE HYGEDASLYL NEIRDFMELR QAMRTPSRNE AGQELLTEYY NQLYFLDQRF
FSPHRNLGIH FHWYDSLTGV PSVQRALAFE KGSVLFNIGA LYTQIGARQD RSTLTGIQNA
IDAFQRAAGA FLYLQENFSH APSLDMSSPA LSMLVRLMVA QVSDVYSLVL QAMSVPLLKD
YVPFSWISMV QVKTHHFRAL AHYYTAVALC DCPGMSDEDE DEGGEIKALI QIHTRRPDKL
DLHDPEDKRR LGKAHLRKAI IRHEEALRLH GVCKMLRKMD ILQEVLSHAH ACSLEKYSDI
DQEDDFCEVA EAPEIQSHTQ QKPDIKTPDF SVVRVTDIFH RLGPLSVFSA RNRWVRRHAC
LVRGETGLGL TLRGDSPVLV AGVLPGGCAA EAGLREGDYI VAVNGADCRW AEHAEVVHAL
KSCTDRALEL DVITIQSHEV ERRMNLSPTG DKECQSGSQR RAGREYERGS SSLWNWSWRS
SGATKRLGST FSLSFGNFRE NESMF
//
