ID A0A498NWS5_LABRO Unreviewed; 2608 AA.
AC A0A498NWS5;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Ankyrin repeat and KH domain-containing 1-like isoform X2 {ECO:0000313|EMBL:RXN36403.1};
GN ORFNames=ROHU_002984 {ECO:0000313|EMBL:RXN36403.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN36403.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN36403.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN36403.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN36403.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN36403.1}.
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DR EMBL; QBIY01008257; RXN36403.1; -; Genomic_DNA.
DR STRING; 84645.A0A498NWS5; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22503; KH-I_ANKHD1; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 9.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR047374; KH-I_ANKHD1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR23206:SF7; ANKYRIN REPEAT AND KH DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1; 1.
DR PANTHER; PTHR23206; MASK PROTEIN; 1.
DR Pfam; PF00023; Ank; 3.
DR Pfam; PF12796; Ank_2; 8.
DR Pfam; PF00013; KH_1; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 25.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 20.
DR PROSITE; PS50088; ANK_REPEAT; 20.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 1: Evidence at protein level;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Coiled coil {ECO:0000256|SAM:Coils};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A498NWS5};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT REPEAT 252..284
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 285..317
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 318..350
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 352..384
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 385..417
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 418..450
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 451..483
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 515..547
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 548..580
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 581..605
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 619..651
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1073..1105
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1106..1138
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1140..1172
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1173..1205
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1208..1240
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1242..1274
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1275..1307
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1310..1342
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1343..1375
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1729..1799
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 715..747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..923
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 929..948
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 954..981
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1461..1490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1505..1685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1699..1723
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1811..1845
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1924..1995
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2029..2238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2376..2406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 771..843
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 729..747
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 898..916
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1521..1558
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1605..1654
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1671..1685
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1699..1714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1818..1845
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1935..1955
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1962..1995
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2033..2062
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2090..2107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2114..2160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2169..2183
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2194..2212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2213..2227
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2608 AA; 275405 MW; 99E28B90752ABCC4 CRC64;
MLTDGFEDEI DSVTPRSPAL GMGVGATPGA GLGGLGIGVG GKKVRLFGEA GGPTTDRLDF
KLTAAAVLSS GPGSGSDEDE VSEVESFILD QEDLDNPVLK TASELLLSSA ADGADLRTVD
PETQARLEAL LEAAGIGKLS TADGKAFADP EVLRRLTSSV SCALDEAAAA LTRMRAENTL
NASQADNRSL AEACSDGDVN AVRKLLDEGR SVNEHTEEGE SLLCLACSAG YYELAQVLLA
MHANVEDRGI KGDITPLMAA ASGGYVDIVK LLLVHGADVN AQSSTGNTAL TYACAGGFLD
VVKVLLKEGA NIEDHNENGH TPLMEAASAG HVEVARVLLE YGAGINTHSN EFKESALTLA
CYKGHLDMVR FLLEAGADQE HKTDEMHTAL MEACMDGHVE VARLLLDSGA QVNMPADSFE
SPLTLAACGG HVELAALLIE RGANLEEVND EGYTPLMEAA REGHEEMVAL LLAQGANINA
QTEETQETAL TLACCGGFLE VADFLIKAGA DIELGCSTPL MEAAQEGHLE LVKYLLAAGA
NVHATTATGD TALTYACENG HTDVADVLLQ TGADLEHESE GGRTPLMKAA RAGHLCTVQF
LISKGKLECA NVNRATANND HTVVSLACAG GHLAVVELLL AHGADPTHRL KDGSTMLIEA
AKGGHTNVVS YLLDYPNNIL SVPAPDLSQL TPPSHDTSQA PRVPFQALAM VVPPQEPDRV
PSTIPTPPPV TSKGASKQRL SSLQSNSVAS GGLDADLLPP FHPYQPLECI VEETEGKLNE
LGQRISAIEK AQLQSLELIQ GEPLTKDKIE ELKKSREEQV QKKKKILKEL QKVERQLQLK
TQQQFTKEYM ETKGVKEELG QAAGVETPGT PLPLQATQLG SDNECEVNRK EEDHRPTPTN
EEDDEDEDEE EDEENIDCAK LPQVNTILSR PATQSPTPPP PQNQVLQSPP LQTSFVPIQP
LTPQQSTDFS NAEYPGSSSP DLQRVLLGQQ LTGLGPGLLA QAPDGLMVAT PAQTLTDTLD
DIMAAVNNRV PGVNTTTSPS PQPSAQTPIN TVSPPSMLPL YPSVDIDAHT ESNHDTALTL
ACAGGHEELV SVLLARGANI EHRDKKGFTP LILAATAGHV GVVEILLDKG GDIEAQSERT
KDTPLSLACS GGRQEVVELL LLRGANKEHR NVSDYTPLSL AASGGYVNII KILLNAGAEI
NSRTGSKLGI SPLMLAAMNG HVPAVKLLLD MGSDINAQIE TNRNTALTLA CFQGRAEVVS
LLLDRKANVE HRAKTGLTPL MEAASGGYAE VGRVLLDKGA DVNAPPVPSS RDTALTIAAD
KGHYKFCELL ISRGAHIDVR NKKGNTPLWL AANGGHFDVV QLLVQAGADV DAADNRKITP
LMAAFRKGHV KVVQYLVKEV NQFPSDIECM RYIATIADKE LLKKCHQCME TIVKAKDQQA
AEANKNASIL LKELDLEKSR EESKKQALAA KREKRKEKRK KKKEEQKRKL EEEEAKVKEV
FCEMQDQKED SAEEVEVPIE PPSATTTTTI GISATSTTFT NTFGKKRANV ATTPSTNRKN
KKNKTKDSPS EPIILQDPQV ALAQQKADKN KIHGEPRGGG APGGTSDSNL DSTDCNSESS
NGSKSQELPD LPSSSSSSAP SILAGTNQPH VASEKRQGLS LPGSREEKVM VSISKPQQKS
HEINSDLTPC SLPPSFKTIS LPVTSPNSKM NLTSPKRGQK REEGWKEVVR RSKKLSVPAS
VVSRIMGRGG CNITAIQDVT GAHIDVDKQK DKNGERMITI RGGTESTRHA VQLINALIQD
PAKELEDLIP RNHIRPPGAN TKISSTYTTS TGATSTTAAS SKGLPSVVPS STVSFQSSTN
FTAQQAGKLG KSMAPGVRPP FVSLPPLAYA HPQLALLAAQ TMNQIRHPRL PMAQFGGTFS
SSPNTWGPFP VRPVSPGSAN SSPKHSGNSA PRPASSAPVH TEHPAASLSS TSTPTGSTTS
PTSTVPASTP TPSSVRKQLF STEPKSGAGV TVASTGSSAP SVQVAASPIS CAPTTPTTPP
PPSAPIAPLP QHPPPPKPEP ASLSTPAKEK PVTELAAPAA GAPSDGPSPS APLHFTSSPS
APSMLPVQPE SRQPLPSHFP SSTESSSSSS SQPGSSHPVT RLPPPTSSNT ITNTSSALPH
YAAPNAPGVS PRMQPPAPYY PMAPGALPEQ QSVFVPPGAS QETLKQQQQQ QPPPQPSLAP
TGMPPPSLPM SSTMGMINGS QMHLHSGKAQ LPPNFGPAAI FNHFSSIFDS NQVGNNQVWG
ACHLPARTPP EQTYSAPTNA YISGMGQIES VIPPPDGSKA PGYRCSSQRI VSSPIGIHPM
DNSMSSSAAL PSFTTSISAS PVFLPGPAPV GTPSFSRQHF SPHPWSASTS CESPVPSVSS
GASSPLCTST VTPALIQAKP SSSNQQDRKV PPPIGTERLA RIRQTGSVNH TMLPTSYTPP
VGQGGIWSFG VGSASETMSG WSQPLMGGPV MHQQMQEPSA FSQHQAMERD DTGIVAPSNT
FHQPLPTNFM DFPKGLPMSM YGGTMIPPHP QMAEGPGGPV YNGLHASDPA WNPILKVVPN
TAENSDPQQV WPGTWAPHVG NVHLNHVN
//
