ID   A0A498NXZ0_LABRO        Unreviewed;       303 AA.
AC   A0A498NXZ0;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Arf-GAP with Rho-GAP ANK repeat and PH domain-containing 3-like protein {ECO:0000313|EMBL:RXN36618.1};
GN   ORFNames=ROHU_002811 {ECO:0000313|EMBL:RXN36618.1};
OS   Labeo rohita (Indian major carp) (Cyprinus rohita).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Labeoninae; Labeonini; Labeo.
OX   NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN36618.1, ECO:0000313|Proteomes:UP000290572};
RN   [1] {ECO:0000313|EMBL:RXN36618.1, ECO:0000313|Proteomes:UP000290572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN36618.1};
RC   TISSUE=Testis {ECO:0000313|EMBL:RXN36618.1};
RA   Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA   Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA   Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA   Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA   Shah T.M., Rai A., Jena J.K.;
RT   "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RXN36618.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QBIY01007636; RXN36618.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498NXZ0; -.
DR   STRING; 84645.A0A498NXZ0; -.
DR   Proteomes; UP000290572; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:InterPro.
DR   GO; GO:0048468; P:cell development; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0048731; P:system development; IEA:UniProt.
DR   CDD; cd04385; RhoGAP_ARAP; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 2.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR037858; RhoGAP_ARAP.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR45899:SF4; ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3; 1.
DR   PANTHER; PTHR45899; RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C; 1.
DR   Pfam; PF00620; RhoGAP; 2.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 2.
DR   PROSITE; PS50238; RHOGAP; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000290572}.
FT   DOMAIN          15..196
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   DOMAIN          207..299
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
SQ   SEQUENCE   303 AA;  35337 MW;  8E634DD1C1499E74 CRC64;
     MWYTDIQKAA GGKGNTLKDQ QLSRNDIPII VDSCIAFITQ YGLGHEGIYR KNGAKSRIKL
     LMEEFRKDAR NVKLRIGDNF IEDVTDVLKR FFREIDDPIF MADLHPFWRE AAKIPQKPQR
     LDRYKELIRG LPRVNRTTLA ALISHLYRVQ KCADLNQMCT KNLSLLFAPS LFQTDGKGEH
     EVKIIEDLID NYLYIFDIDE EHQTQIELEI SLITTWRDTQ PQRLDRYKEL IRGLPRVNRT
     TLAALISHLY RVQKCADLNQ MCTKNLSLLF APSLFQTDGK GEHEVKIIED LIDNYLYIFD
     VSE
//