ID A0A498P0N8_LABRO Unreviewed; 1753 AA.
AC A0A498P0N8;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=ATP-binding cassette sub-family A member 1-like protein {ECO:0000313|EMBL:RXN37775.1};
GN ORFNames=ROHU_035912 {ECO:0000313|EMBL:RXN37775.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN37775.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN37775.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN37775.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN37775.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN37775.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QBIY01005449; RXN37775.1; -; Genomic_DNA.
DR STRING; 84645.A0A498P0N8; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF234; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 1-LIKE; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 3.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:RXN37775.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 632..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 679..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 748..768
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 788..812
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 824..847
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 853..875
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 927..950
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1359..1381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1691..1713
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1008..1195
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1753 AA; 195958 MW; 6888E4EFD1C54169 CRC64;
MYPNRRSVTF EEEEGKRVHI PIATCQRAIM SLLTQLRLLL WKNFTLRRRQ KNSTRTGILM
VKKVQSKGHY PNKPLPSAGV LPWLQGMFCN IQNPCVSFPT PGEAPGQVNN FDNSTVTKVL
VEVQSLLADP ALLSSVKLIS DDIGRWTSVL QNANPAAGQS IPLRSLLRTN ETFSEYLMNN
LSVPNTTAAS LMRARVRLGQ FPALSAEGDL RSVLCGPSID RILEFNSANE KVEFQNITCS
LTANQLLQAR RVFTQNLDNM KLLNELPLAL GLNRLEVAVL MAQTSTHIAP LVAGEHNLQR
VQIIGSNHLM SSFICLHLKV LHKRTTNAQR QTDTTSDTTH RKASVCSRSE FCKNLTETLE
STSSLRLLWK TFQPFLQGKV LYAPDTNVTR SIMTEANRTF DALAKVGELA EAWLENEDVI
WDFFNNSTQI NSLRALLKNP VLTAVLDQQL EEGGLSTALI SNFLFNGPES ERPAGMPAFD
WRNVFNTTSG AAQQLTQILS CFDLDKFEGV STEALLVEQA LKLLSQGHYW AGLVFTDLNP
SDPLTPPHIK YKIRMDIEET ERTDKTKERS WYPSARANPL NDLRYVSGGF VYLQDMVDRG
IVKVQTGVSQ PLGVYAQQMP YPCYMDDAFT SYIGTMLPMF LVLAFINSAS LIIKNLVLEK
ELRLKEVLRV VGVRNSSMWF CWFIENMILL AIPCALISVL VKLACYGPII GVLIISSVII
QHSQPVTFRN SFIASSFPWF LRSLTRSLPL YMTLAWIFSV ALIVKGVVQE KEARLKETVR
MMGLKGSTYW LSWTISSMLP LAVSAALLTV ILKYGKVLRY SDPSVIFVFL LVFCVATVMQ
CFFISVFFSR ANLAAACGGL IYFLLYLPHV LCYAWRDVLG FGAKIATSLL SCVAFGYGCE
NFSRYEEQGI GIQWSNIRVS PQENDRYSFI VSIFMMLFDA FIYWILTWYI ENVYPGQYGI
PKPWYFPFTS SYWCGTRVGS DAEPDLLHEM ENQKGFLEKP PPGMKPGVCI RNLVKVYKTG
NKLAVDGLSL DFYQDHITSF LGHNGAGKTT TILTVEEHIY FYARLKGRSS KEVKKEIDQM
IKDVGLPHKR NDLAKNLSGG MQRKLSVAIA FVGGSNVVIL DEPTAGVDPY ARRGIWELLL
KYKKGRTIIL STHHMDEADI LGDRIAIISH GRVCCCGSSL FLKKTYGRGY YLTIARANQD
RVAGRVPTIR ECDKNSIDEG ICSDSISSLD PPDAADLSRL VRRHVPEAEF LEVVGQELVY
VLPYAGATNG SFASLFKDLD LEKGALGVTS YGISDTSLEE IFLKVAEDTG VDVESHDTQR
PMCENGKGSY TITGWSLIKQ QFIALFIKRF HHARRSRRGI IAQVVMPAFF VCLALIFSLI
VPPFVEYPSL ELQPWIFDDP GVDQVKRVTN ALLSSPGFGT RCMSTNPIPK LPCNPAGGTD
WFTPAVDPSV SEIFEKGNWS MENPSPDCQC STPQRSIILP DCPLGAGGLP PPQVRHTHTH
TLVNGHWLQL YTIANYGLHI ADAALCQWLL CLSKVKTQNT TDTLQNLTAR NMTDFLIKSY
QKSGKIRYGG VSVGGVNSQV KLNESDITAL IDDLKSVLNI SQFNQTEPIF QAIQLFLLEL
GTRDNVKVWF YNQGWHSLVS FLNVASNSIL RGNLPAGRRA EEFGITTFNH PLNLTKEQLS
FAALATTSTD VVVSICVIFA MSFIPASFVL FLIQERVSKS KHLQFVSGVN PTIYWLANFA
WDMVRYVSSV LLH
//
