ID A0A498P1Q2_LABRO Unreviewed; 403 AA.
AC A0A498P1Q2;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=ROHU_001422 {ECO:0000313|EMBL:RXN38113.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN38113.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN38113.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN38113.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN38113.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN38113.1}.
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DR EMBL; QBIY01005137; RXN38113.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498P1Q2; -.
DR STRING; 84645.A0A498P1Q2; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF416; CARBOXYLESTERASE 3; 1.
DR Pfam; PF00135; COesterase; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 2.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 2.
PE 1: Evidence at protein level;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A498P1Q2};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..183
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT DOMAIN 283..401
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 403 AA; 43796 MW; 7F26B585B9794995 CRC64;
MLTDNSAASG VIPALTSLPS RVFQRMLNLM LATSSVIPLG LLCMWTLQFW LKAQLYDDRL
PFSTGDEHAP GNYGLLDQVA ALQWVQENIH SFGGDPGLVT IFGESAGGIS VSLHVLSPLS
ANLFHHAIAE SGTAAMDGIP NPNPLPIAQA VGNLSGCDIS STKKIVDCLM QLTEDDILKI
TLFFSPPGWT DGMDMEQIMP ILTMFNPILR DESVAELVLN EYLGASPDRI KIRDGFREML
GDFIFNIPVR KLANYHRGEL LEEENELCKT VMGYWGNFAR TGTGDEHAPG NYGFLDQVAA
LQWIQENIHS FGGDPGSVTI FGESAGGMSV STLILSPLAS GLFHRAIAES GTAFWDGFVM
GNPLLRAQNT AKLCKCDSSS SSEIVDCIMR WSEEEVLECS NQV
//
