ID A0A498P268_LABRO Unreviewed; 340 AA.
AC A0A498P268;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 28-JUN-2023, entry version 11.
DE SubName: Full=Kazal-type serine protease inhibitor domain-containing 1-like protein {ECO:0000313|EMBL:RXN37644.1};
GN ORFNames=ROHU_001861 {ECO:0000313|EMBL:RXN37644.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN37644.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN37644.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN37644.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN37644.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN37644.1}.
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DR EMBL; QBIY01005571; RXN37644.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498P268; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR CDD; cd00104; KAZAL_FS; 1.
DR Gene3D; 3.30.60.30; -; 1.
DR Gene3D; 4.10.40.20; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR000867; IGFBP-like.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR21258:SF14; DOCKING PROTEIN 2; 1.
DR PANTHER; PTHR21258; DOCKING PROTEIN RELATED; 1.
DR Pfam; PF00219; IGFBP; 1.
DR SMART; SM00280; KAZAL; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51323; IGFBP_N_2; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..340
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019760196"
FT DOMAIN 50..129
FT /note="IGFBP N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51323"
FT DOMAIN 104..167
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
SQ SEQUENCE 340 AA; 38069 MW; 519378983DF141CC CRC64;
MLMHIVTFAV LVLSIRTAHG FPNYKDDYMD EDLATFDYYK GTDEFDERNR TQECEECVPE
LCPLLLGCRA GLVQDSCGCC SQCANLEGQT CDLGQRTVYY GLCGENLECK LDRSDGADGE
EPETQCVCLS QKPLCGTDGQ TYMNICKYKE AAYSNPGLNV SDGPCRTGHK HRDPTLRYMC
LQKWRKVWSV LYRESSCSIS RLEFFEFKDG AGNTLEKANR KQENKKVIKM NDCIRVSEAD
VEGCPRDCGP FLVETTEKTF VFAVETAELE DWIQKLCEIA FPMSWTERGA VRGNSLHGES
DDVTMADNTL YCSRETGSAI LSFAARCGVF ASVLTAANRS
//
