ID A0A498P522_LABRO Unreviewed; 341 AA.
AC A0A498P522;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 22-FEB-2023, entry version 9.
DE SubName: Full=Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 {ECO:0000313|EMBL:RXN38537.1};
GN ORFNames=ROHU_001021 {ECO:0000313|EMBL:RXN38537.1};
OS Labeo rohita (Indian major carp) (Cyprinus rohita).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Labeoninae; Labeonini; Labeo.
OX NCBI_TaxID=84645 {ECO:0000313|EMBL:RXN38537.1, ECO:0000313|Proteomes:UP000290572};
RN [1] {ECO:0000313|EMBL:RXN38537.1, ECO:0000313|Proteomes:UP000290572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DASCIFA01 {ECO:0000313|EMBL:RXN38537.1};
RC TISSUE=Testis {ECO:0000313|EMBL:RXN38537.1};
RA Das P., Kushwaha B., Joshi C.G., Kumar D., Nagpure N.S., Sahoo L.,
RA Das S.P., Bit A., Patnaik S., Meher P.K., Jayasankar P., Koringa P.G.,
RA Patel N.V., Hinsu A.T., Kumar R., Pandey M., Agarwal S., Srivastava S.,
RA Singh M., Iquebal M.A., Jaiswal S., Angadi U.B., Kumar N., Raza M.,
RA Shah T.M., Rai A., Jena J.K.;
RT "Draft genome sequence of Rohu Carp (Labeo rohita).";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXN38537.1}.
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DR EMBL; QBIY01004754; RXN38537.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498P522; -.
DR STRING; 84645.A0A498P522; -.
DR Proteomes; UP000290572; Unassembled WGS sequence.
DR CDD; cd12924; iSH2_PIK3R1; 1.
DR CDD; cd09942; SH2_nSH2_p85_like; 1.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 2.
DR InterPro; IPR044124; ISH2_PIK3R1.
DR InterPro; IPR032498; PI3K_P85_iSH2.
DR InterPro; IPR035022; PI3kinase_P85_nSH2.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF3; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA; 1.
DR Pfam; PF16454; PI3K_P85_iSH2; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00678; PI3KINASEP85.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 2.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000290572};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 1..100
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT COILED 114..148
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 186..234
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 341 AA; 40709 MW; 90BE7102FC167E74 CRC64;
MNNNMALQDA EWEEVNEKLR DTADGTFLVR DASTKMHGDY TLTLRKGGNN KLIKIFHRDG
KYGFSDPLTF NSVVELINHY RHESLAQYNP KLDVKLLYPV SKHQQDQVVK EDNIEAVGKK
LHEYHQQYQE KNREYDRLYE EYTRTSQEIQ MKRTAIEAFN ETIKIFEEQC QTQERYSKEY
IEKFRREGNE KEIQRIMVNY EKLKSRISEI VDSKRRLEED LKKQAADYRE IDKRMNSIKP
DLIQLRKTRD QYLMWLTQKG VRQKKLNEWL GIKNDNQDDV DGEVKHCVIN KTPTGYGFAE
PYNLYSSLKE LVLHYQHTSL VQHNDSLNVT LAYPVYAHQR R
//
