ID   A0A498RF11_9FIRM        Unreviewed;      1048 AA.
AC   A0A498RF11;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Acriflavin resistance protein {ECO:0000313|EMBL:VBB07768.1};
GN   ORFNames=LUCI_3033 {ECO:0000313|EMBL:VBB07768.1};
OS   Lucifera butyrica.
OC   Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC   Lucifera.
OX   NCBI_TaxID=1351585 {ECO:0000313|EMBL:VBB07768.1, ECO:0000313|Proteomes:UP000277811};
RN   [1] {ECO:0000313|EMBL:VBB07768.1, ECO:0000313|Proteomes:UP000277811}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LUCI {ECO:0000313|EMBL:VBB07768.1};
RA   Strepis N.;
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UPPP01000080; VBB07768.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498RF11; -.
DR   OrthoDB; 8270at2; -.
DR   Proteomes; UP000277811; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF21; MULTIDRUG RESISTANCE PROTEIN MDTB; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277811};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        340..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        391..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        435..461
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        467..494
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        533..551
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        865..884
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        917..945
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        966..985
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        997..1021
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1048 AA;  114293 MW;  AE48B434E7148A4C CRC64;
     MNISAIWIRR PVMTILIMIT LLSFGVISYW KLPVNDLPDV DYPAIQISAS LPGANPETMA
     SSVALPLEKQ LSTISGVDSM TSISYTGTTT ISMTFSLDRD IDGAANDVSA AISAATKRLP
     TNMPSPPTYT KTNPANQPVM YYVVSSKTMK MPEIEDYVQS QLIPAVSAVN GVSQALIFGQ
     AQYAVRLRMD PDKMAVRGVG INEVSNAIIN GNVNLPGGTL NGPDVTYNID SSGQLMNAKE
     YNSLIVAYHN GNPIRLRDIG KATDSSENEK IVKNVITPGE EAPGVLVAIF KQPGSNAVQI
     ASDVRKKMET VKKSLPQSLT VSLLYDKANF IHASVDDVEA TLALTVLLVI CVVFLFLGSL
     RATLIPGITV PLSLMATFAI MKISGFSLNT ISLMALSLAA GFVVDDAVVV MENIVRRVEK
     GETPMAAAFS GSREICFTIL SMTISLVVVF VPILFMSGII GRLFREFAVS IAAAILFSGF
     ISLTLTPMMC AYIIKPKNGD SKPSRIMEIS ERVFERARNF YGQTLTITLN HPLRVLVFIL
     GVFVLAGFLY TKIDKGFIPS QDMDMFTIRT QADDRSSFDY LKNHQEEINK ILEKLPGLRG
     AVSTVGSPTY NTGFIIVSLE DRKNRAESVD QIINRLRPEF NNVPGLRVTS YNPPPISMGS
     RQSYGVGQYT ITSPNLDLLY KAANDMETQI KTIPGITDVV SSLQTKVPTM YLTIDRDKAS
     ALGLSANQIQ DALYSAYGDR QVSTIYSASN EYDVFLDLGV NFQTDPSVLN KLYVKTGSSL
     GPSVTTPALV PLSTIGKLTQ TMMPLSINHS GQMPSATIQF NLKPGYALGT AAAEIQTLAQ
     KTLPSSVVGF FEGNASAYQS SFKNMGFLLL ITVFLIYVVL GILYESFIHP ITILTALPLA
     GAGALIFLML FHMELDIYSY VGIIMLIGLV KKNGIMMVDF ALELAEKQGL PSKEAIHQAC
     LIRFRPIMMT TMAAVFGALP IALGYGSGGE ARQPMGIAVV GGLVFSQFLT LYVTPVFYVW
     FDHLQQKLKA RRQETERYVP PRRRQMFE
//