ID A0A498SAS2_ACAVI Unreviewed; 1084 AA.
AC A0A498SAS2;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=EGF-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=NAV_LOCUS3605 {ECO:0000313|EMBL:VBB28775.1};
OS Acanthocheilonema viteae (Filarial nematode worm) (Dipetalonema viteae).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Acanthocheilonema.
OX NCBI_TaxID=6277 {ECO:0000313|EMBL:VBB28775.1, ECO:0000313|Proteomes:UP000276991};
RN [1] {ECO:0000313|EMBL:VBB28775.1, ECO:0000313|Proteomes:UP000276991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; UPTC01000471; VBB28775.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498SAS2; -.
DR STRING; 6277.A0A498SAS2; -.
DR Proteomes; UP000276991; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00110; LamG; 2.
DR Gene3D; 2.60.120.1000; -; 1.
DR Gene3D; 2.60.120.200; -; 3.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR15036:SF85; SP2353, ISOFORM A; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF00054; Laminin_G_1; 1.
DR Pfam; PF02210; Laminin_G_2; 2.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00282; LamG; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 4.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS50025; LAM_G_DOMAIN; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000276991};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1019..1045
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..211
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 367..404
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 611..785
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 781..818
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 394..403
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1084 AA; 122928 MW; 1475195134F3DAC7 CRC64;
MDSLFVLNIT VQIKLILVQK KKKESLGHLK DENDGKNEIT ESTPISYFND NMYFVDAHKV
GIVSTYENHL IIMFRTFENG IFIFSMAEQG DLLIAQIIHG KIFIIFDFGS LTRTTISGGT
ALNDGEWHEI RWIHQFDSVQ LYVDGVIMNT TIPSGLYRKL DFDSKIYIGG RPVDDDMNID
IETSYHGCFA RVVLNNIDLL AEIPRSLRKD CQIPKSHPMT IMTGGYVTIP FSFLPFSIEF
RILPQPSSIL LLTDANNKSL AQIALNRKGL LVLTLFTNMS EVEQLSQSGK LVNDSSWHSL
SLMIWGARLH VDVDSYTVLW SEGNVIRNLA KQLTHFHLSA VGCYRSATTA FKSSNLIGNV
TLDACHFQER CLPNPCENHA ICKQISLNDF SCNCRASYYG KTCHATRKYH SCEEFFLKNQ
HIKSKNVTID LDGGNPLEPF TVQCEQNFKD YDNIRITSKI FHQFGNSDII INGDYEPGSV
KRSFDYGITI NQLDRFIDGF ENCVQYMRYE CRGGAKLMIY GTEGRPSSWY STRNGQHAMQ
WGDAPPYSRM CPCAANLSCT HNRMCNCDSG EDGVDEGYNP HMQLLPVMNL YLGGTTATSS
INVFIGPLIC SERHVFDGIT FLNRNARLAG SQALFGSVMD LEFQIRMSHA QMTIFIWESL
NGQRWYQLDL TDGRLVGQVV SGSKVFEIQS KMRINDNRWH TVYWEVNING MMLNVDNESI
LLDVYVIPPN VYTWIIGSRS ERGLSGFAGQ IRNMYLCGNE IMLQSLVRKQ GRGMRGIEIG
EKGTCKRDDC LNHGQCIEFY DNHKCSCDNT PFIGQKCDQD VSIFVPKDSE LTIPWQNPAQ
VSSCFRIAVQ SFSSNYSLIK AKALFADCQF NLTINQKGYL ELSVFDGFFF HYKATDITHK
FGDNELTDVN FCAEKTEFTL QINGEDVFHI NGNWSFFPQL NVWKFIDKNF TGCLTRLQVG
ISFPLKDPSS SRLLYKGGIR FEGCPHNHIF FNQIPKEEEK SSLPNIHINA IIEHRASPLA
LAPIIAVVTG CSLFLLILLV GICWIRNRPD GVYKTNEDIL AYCSPNRSGE PLVAINCIDR
EYYC
//
