ID A0A498SC68_ACAVI Unreviewed; 861 AA.
AC A0A498SC68;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 8.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=NAV_LOCUS4523 {ECO:0000313|EMBL:VBB29728.1};
OS Acanthocheilonema viteae (Filarial nematode worm) (Dipetalonema viteae).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Acanthocheilonema.
OX NCBI_TaxID=6277 {ECO:0000313|EMBL:VBB29728.1, ECO:0000313|Proteomes:UP000276991};
RN [1] {ECO:0000313|EMBL:VBB29728.1, ECO:0000313|Proteomes:UP000276991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the patched family.
CC {ECO:0000256|ARBA:ARBA00005585}.
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DR EMBL; UPTC01000681; VBB29728.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498SC68; -.
DR Proteomes; UP000276991; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR PANTHER; PTHR10796:SF193; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02460; Patched; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000276991};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 190..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 500..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 694..720
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 727..747
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 753..778
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 799..822
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 828..852
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 196..355
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 861 AA; 98130 MW; B3603FC5246677E1 CRC64;
MRITSIEPQL RRFFQWYGEF GYQWRWFLVM TPLIITPLLS LGFCRLTPLT VDDPFYVFTP
VFARWHREFD TFASLWPLNE NKFLPGKSFE VKRFINILIK AKDGDNLLRR QILDEIQGLN
QWIMFNITVP TADGKYNLTY QDLCLSYEWV CGANEHISML QERLRIGNFM ELTYPRAGSK
DGLAENAKDF TWNFLTSFSL LSIYATIFSY VLKKQPRVSI DWIRSKPYIA CAGLITTLLA
ICSGFGLALI LGIPYNVINT IIPFLIIAVG VDDMFVMNAC WNQTSQTDTV SKRMRDMMGH
AGVTISITNI TDILSFAVGC VSELPGIQLF CSYACITFIF CYLYQFTFFM AFLAIMGAVE
KNRRHCLLFY KISEQYAKKE IINSAQFCNS RNEYKDSLRC SSTDSGSDMS YRSGISIQSD
SSSLKTSIKN FNLIIVADDL CKQKPTEIVD IDNNFITKGL CMTALPHLKT QPTGKKENTC
TQYFFGHIYA PFILRKECAI LTYIFYCIYI AVAVIGCLNY SEGLEPENLV TNDHYSSHYF
ADLKNFWIRG AQLHVAVLHP PNFTDPIQRE KMMAVVRAFE NTEYTLGRDG TIFFFLEYLN
YLDEVNAELE NTERIWNTKL LSWLKYTGGS NQWATDIRFN ENGTFQAFRF QIAMHNTVGA
NQHKNAARKL REIADRQPFK IEVFHETFPF ADQYIIIVPV TIRSIIISLI CMATVAIMLI
PSLIPCVLII ISIISINTGI FGYMTFWGVN LDAVSMISII MSIGFAVDLS SHITYAFVTA
TGSSKERVIH ALGSLGWPIF QGAASTITGV TVLYTVNAYI ILTFFKTIWL TMVIGLLHGL
LFIPVTLCFF PLSSFQLSSK L
//
