ID   A0A498SFC4_ACAVI        Unreviewed;       359 AA.
AC   A0A498SFC4;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=Transmembrane protein 120 homolog {ECO:0008006|Google:ProtNLM};
GN   ORFNames=NAV_LOCUS5177 {ECO:0000313|EMBL:VBB30386.1};
OS   Acanthocheilonema viteae (Filarial nematode worm) (Dipetalonema viteae).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Acanthocheilonema.
OX   NCBI_TaxID=6277 {ECO:0000313|EMBL:VBB30386.1, ECO:0000313|Proteomes:UP000276991};
RN   [1] {ECO:0000313|EMBL:VBB30386.1, ECO:0000313|Proteomes:UP000276991}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TMEM120 family.
CC       {ECO:0000256|ARBA:ARBA00009700}.
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DR   EMBL; UPTC01000861; VBB30386.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498SFC4; -.
DR   Proteomes; UP000276991; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR012926; TACAN/TMEM120B.
DR   PANTHER; PTHR21433:SF0; TRANSMEMBRANE PROTEIN 120 HOMOLOG; 1.
DR   PANTHER; PTHR21433; TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA; 1.
DR   Pfam; PF07851; TMPIT; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000276991};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        137..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        162..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        193..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        223..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        267..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        308..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   359 AA;  42377 MW;  959F3018336264DD CRC64;
     MGDDESPFER VFDEWRSLKD EFEGIEDRHR IYLGKLKQLS KLQDDCQKAV RHCLYQISKI
     REALRGLKGK EQPESAEYLK KVKEGIAELE RRSQDMKGEL PVQDNGLYLS IILGSNLNVS
     LMNKNDRYRY KQEYEKFKVT VNCTLLFVLF LAYIFTSRIL DLVINFMLVW FYCTLTIREA
     ILRINGSRIK GWWIMHHYVS CVLSGITVTW GDGECYRSIR TQFIMFCFFL FFVQLLQCRY
     QNGCLRRLHA LGQRYSMDIS VEGFSSWMFK GLTFLIPFLM LTYVFQFYNS YKLYYLSKAP
     ICVNQWQVLI LAYGFFLVAC CNVFTLLSVV VNKWKQGQRM STLIALRSKY STISPSKEE
//