ID   A0A498SS51_ACAVI        Unreviewed;       884 AA.
AC   A0A498SS51;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   ORFNames=NAV_LOCUS7689 {ECO:0000313|EMBL:VBB32898.1};
OS   Acanthocheilonema viteae (Filarial nematode worm) (Dipetalonema viteae).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Acanthocheilonema.
OX   NCBI_TaxID=6277 {ECO:0000313|EMBL:VBB32898.1, ECO:0000313|Proteomes:UP000276991};
RN   [1] {ECO:0000313|EMBL:VBB32898.1, ECO:0000313|Proteomes:UP000276991}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the importin beta family. Importin beta-1
CC       subfamily. {ECO:0000256|ARBA:ARBA00010907}.
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DR   EMBL; UPTC01002005; VBB32898.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498SS51; -.
DR   STRING; 6277.A0A498SS51; -.
DR   Proteomes; UP000276991; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   PANTHER; PTHR10527:SF1; IMPORTIN SUBUNIT BETA-1; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000276991}.
FT   DOMAIN          24..104
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   884 AA;  98020 MW;  61E80A66545510C6 CRC64;
     MAQEELLEVL QRTASLNPND QTLALDYLRR ACVSNFPEFT KQLSTVLATP SYSNFVRQAA
     GLQLKNVLVA KEDATKNEYL TRWLALPIDV REFVKQNVVR TLGTEPFRPS IAAQCVAAIA
     CAEIPSQMWP DVITHLRDSV IATSNSEILR EASLEALGYI CQDICGSLLE RESNQILTAI
     VHGLRKDEPS NHIRLAAANA MLNSIEFTKH NFSRENERHM IMQVVCESSQ CPETAVKVVA
     MQCLVRIMSL YYQFMEQYMD ALFPISLNAM KSQINEVALQ GIEFWSNVCE EEISLSVEAE
     EAREQGRAPE NVSRHYARGA LTHLIPILTE TLAKQEESDD EDDWNPAKAA GVCIMLLAQC
     TGDSIVEPIL PFIQQHLKNP SWRYREASIM AFGSILDGPN EAVLTQLVES ALTSIIGSLS
     DPQLQVRDTA AWCIGRVCDT CEEVVIRQEI LAPMLPALST ALQQEPRVAA NVCWAISSLA
     KAAFDMACRQ GTDNSGQPET YILSSCFEGM VNELIKATDR PDAHVSNLRI AAYETLMELI
     KNSPKDCYHV VQNTTVIVLR KLEQLLNIEN SLESLSDKSQ LRDLESLLCA TLQSVLRKMR
     PEDTPYIGDA IMQGLLQIMQ RCAGKECGGV MEDALMAVST LIEALGCQFS TYLDVFKPFL
     IAGLQNHEEG QVCSAAIGVL VDLCRALEAA LMPHLDEFMG LLFQIVQSNK IDRLVKPAVL
     SCFGDVALAI GPNFSRYYEY VMAMLVMALS TAKVEDPEDY DNVEYVEQLR ESCVEAYAGI
     VQGMRTTQNN EFQQLQDQIQ NMLGLIELIA TCNSPDSLIG AASGLLGDLV TSFGEQILPF
     VDNQNISAIL TKGRRSKAAK TKSLALWATK EIRKLKTAKM ENHS
//