ID   A0A498STV2_ACAVI        Unreviewed;       313 AA.
AC   A0A498STV2;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Guanine nucleotide-binding protein alpha-12 subunit {ECO:0008006|Google:ProtNLM};
GN   ORFNames=NAV_LOCUS7020 {ECO:0000313|EMBL:VBB32229.1};
OS   Acanthocheilonema viteae (Filarial nematode worm) (Dipetalonema viteae).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Acanthocheilonema.
OX   NCBI_TaxID=6277 {ECO:0000313|EMBL:VBB32229.1, ECO:0000313|Proteomes:UP000276991};
RN   [1] {ECO:0000313|EMBL:VBB32229.1, ECO:0000313|Proteomes:UP000276991}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UPTC01001607; VBB32229.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498STV2; -.
DR   STRING; 6277.A0A498STV2; -.
DR   Proteomes; UP000276991; Unassembled WGS sequence.
DR   GO; GO:0001664; F:G protein-coupled receptor binding; IEA:InterPro.
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:InterPro.
DR   CDD; cd00066; G-alpha; 1.
DR   Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR000469; Gprotein_alpha_12/13.
DR   InterPro; IPR001019; Gprotein_alpha_su.
DR   InterPro; IPR011025; GproteinA_insert.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR   PANTHER; PTHR10218:SF362; GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA HOMOLOG; 1.
DR   Pfam; PF00503; G-alpha; 1.
DR   PRINTS; PR00318; GPROTEINA.
DR   PRINTS; PR00440; GPROTEINA12.
DR   SMART; SM00275; G_alpha; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR   PROSITE; PS51882; G_ALPHA; 1.
PE   4: Predicted;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000276991};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224}.
SQ   SEQUENCE   313 AA;  37280 MW;  B40CEA4EC6B58FCC CRC64;
     MVIINGRGEF TADEVRAYRQ QIYQKVENLQ NIITAMRVLL DARQKLGYAW KNPERQRNVD
     AIMRFTASDM MRGIDQSTFA EMAPLIRDFW EDASIKQTYE QRNLFQISDS CMYFFDHINR
     VAMPDYCPTN RDILFCRKAT RGITEHVFEI QRVSFRFIDV GGQRSQRQKW FQCFEGITSI
     LFMVASCEYD QVILEDRRTN RVAESRSVFE TIVNNKSFAN VSIILFMNKS DLLEEKVSKS
     DIRQYFADFT GDHNNLRDVQ FFLVDKFENC RRDRRRPFFY HFTTAVDTEN IRRVFNDCRE
     TILEQNLKAL MMQ
//