ID   A0A499FTG1_ANOAR        Unreviewed;       599 AA.
AC   A0A499FTG1;
DT   03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   03-JUL-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Anopheles arabiensis (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7173 {ECO:0000313|EnsemblMetazoa:AARA018400-PA.1, ECO:0000313|Proteomes:UP000075840};
RN   [1] {ECO:0000313|Proteomes:UP000075840}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AARA018400-PA.1}
RP   IDENTIFICATION.
RC   STRAIN=Dongola {ECO:0000313|EnsemblMetazoa:AARA018400-PA.1};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the glycoside-pentoside-hexuronide (GPH) cation
CC       symporter transporter (TC 2.A.2) family.
CC       {ECO:0000256|ARBA:ARBA00038193}.
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DR   EMBL; APCN01003453; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A499FTG1; -.
DR   EnsemblMetazoa; AARA018400-RA; AARA018400-PA; AARA018400.
DR   VEuPathDB; VectorBase:AARA018400; -.
DR   VEuPathDB; VectorBase:AARA21_000672; -.
DR   Proteomes; UP000075840; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:UniProt.
DR   CDD; cd17313; MFS_SLC45_SUC; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR19432:SF35; LP09277P-RELATED; 1.
DR   PANTHER; PTHR19432; SUGAR TRANSPORTER; 1.
DR   Pfam; PF07690; MFS_1; 2.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ   SEQUENCE   599 AA;  65463 MW;  0649CED4993B46AC CRC64;
     MVKTGPGGGP SAASGRVVLA RRKSLAQKDP LVEELRKARE ENARQQQYDY SHVFRKKTLL
     DFVRLSFVIM GIEIVYSAET AFVTPILLGI GIEHQLMTIV WGISPLIGFI VSPFLGTFSD
     RCRSRFGRRR PLLVVLGMGL VLGCLLLPFG ETIGHWLGDT GESEKPVINN TVTIGGNRNP
     YGSATASIAH YKWAIVVTIL GTILLDFCAD SSQAPSMAYL LDVSLPDDHG QACSTYSLLS
     GVGGCIGYLI GAIDWNGTML GELLGGNINT VFILVTVIFV LCLAVTVGSF REIPLPLMER
     DELLQPLTER AVTEQRQRTT VEKGLRPMKD IADALLLELE GDDSEPSDRT VLLSYSEKEP
     LMGDFLQEKP KSSAKEFLRI TFRIPATLAV LCVTNLFCWM SHISYSLYFT DFVGEKVFGG
     DPMAHSDSDE YALYIEGVRY GCFGMAIYSI ACSTYSCTIE RLIRVFRARN VYSGGLLIDF
     VGMLLMAMFP SKVTVYVFSV TGGIVGALLF TMPYIILAKY HAKGLLDTCD ETNSIQPRRG
     LASDISIIGS MLFVAQIILS LTMGPLVTLT GTTASVIYTA SVCSLVASLC ATQIQYLDL
//