ID A0A4D6B286_9CAUD Unreviewed; 441 AA.
AC A0A4D6B286;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=Javan374_0048 {ECO:0000313|EMBL:QBX27239.1};
OS Streptococcus phage Javan374.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Trabyvirinae.
OX NCBI_TaxID=2548134 {ECO:0000313|EMBL:QBX27239.1, ECO:0000313|Proteomes:UP000296403};
RN [1] {ECO:0000313|EMBL:QBX27239.1, ECO:0000313|Proteomes:UP000296403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Rezaei Javan R., Ramos-Sevillano E., Akter A., Brown J., Brueggemann A.B.;
RT "Prophages and satellite prophages are widespread among Streptococcus
RT species and may play a role in pneumococcal pathogenesis.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily.
CC {ECO:0000256|ARBA:ARBA00008428}.
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DR EMBL; MK448921; QBX27239.1; -; Genomic_DNA.
DR Proteomes; UP000296403; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-KW.
DR CDD; cd00984; DnaB_C; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR036185; DNA_heli_DnaB-like_N_sf.
DR InterPro; IPR007692; DNA_helicase_DnaB.
DR InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR InterPro; IPR016136; DNA_helicase_N/primase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00665; DnaB; 1.
DR PANTHER; PTHR30153:SF2; REPLICATIVE DNA HELICASE; 1.
DR PANTHER; PTHR30153; REPLICATIVE DNA HELICASE DNAB; 1.
DR Pfam; PF00772; DnaB; 1.
DR Pfam; PF03796; DnaB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF48024; N-terminal domain of DnaB helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51199; SF4_HELICASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000313|EMBL:QBX27239.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:QBX27239.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Primosome {ECO:0000256|ARBA:ARBA00022515};
KW Reference proteome {ECO:0000313|Proteomes:UP000296403}.
FT DOMAIN 176..441
FT /note="SF4 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51199"
SQ SEQUENCE 441 AA; 49151 MW; CD0FA759A54631D5 CRC64;
MAENMNVLPH DLLAEQAVLG SIFLDPDKIH IASEYLTKDS FFKLSHGMVF NIMQELSDKG
DPIDPVSVKS ALDSIGQFEQ IGGMPFLASL INAVPTSAHI EHYSKVVAEK SRARKVIEDL
SHSISSVYDG QKDLNEILSQ TEQNLSTISN EQKKGFRPII DVIDSTQSIL DERSQKVGDV
TGTSTGFTDF DQITTGLHED NLIIIAARPA MGKTAFALNI AQNVAKNSDK AVAIFSLEMG
AESLVERMLS AEGLIPSYHV RTGNLTESEW RRMISAQERL ARGKIFIDDT AGVKISEIRS
KAKRLAQEND GLGLIVIDYL QLIEGRGREN RQQEVSEISR QLKILAKELK VPVIALSQLS
RGVDQRNDKR PILSDLRESG SIEQDADIVA FLYREAYYKR DEQEEPDNVT ELILEKNRHG
SLGTVQLFFL KEYAKFSNKE A
//
