ID A0A4D6HGM8_9EURY Unreviewed; 179 AA.
AC A0A4D6HGM8;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=pyruvate synthase {ECO:0000256|ARBA:ARBA00012822};
DE EC=1.2.7.1 {ECO:0000256|ARBA:ARBA00012822};
GN ORFNames=DV733_16620 {ECO:0000313|EMBL:QCC52755.1};
OS Halapricum salinum.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halapricum.
OX NCBI_TaxID=1457250 {ECO:0000313|EMBL:QCC52755.1, ECO:0000313|Proteomes:UP000296706};
RN [1] {ECO:0000313|EMBL:QCC52755.1, ECO:0000313|Proteomes:UP000296706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBA1105 {ECO:0000313|EMBL:QCC52755.1,
RC ECO:0000313|Proteomes:UP000296706};
RX PubMed=30975999; DOI=.1038/s41467-019-09390-9;
RA Xiong L., Liu S., Chen S., Xiao Y., Zhu B., Gao Y., Zhang Y., Chen B.,
RA Luo J., Deng Z., Chen X., Wang L., Chen S.;
RT "A new type of DNA phosphorothioation-based antiviral system in archaea.";
RL Nat. Commun. 10:1688-1688(2019).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA
CC + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]; Xref=Rhea:RHEA:12765,
CC Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001, ChEBI:CHEBI:15361,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:33737,
CC ChEBI:CHEBI:33738, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=1.2.7.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001135};
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DR EMBL; CP031310; QCC52755.1; -; Genomic_DNA.
DR RefSeq; WP_049993075.1; NZ_CP031310.1.
DR AlphaFoldDB; A0A4D6HGM8; -.
DR STRING; 1457250.GCA_000755225_02205; -.
DR GeneID; 39849517; -.
DR KEGG; hsn:DV733_16620; -.
DR OrthoDB; 372091at2157; -.
DR Proteomes; UP000296706; Chromosome.
DR GO; GO:0016625; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor; IEA:InterPro.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR InterPro; IPR011894; PorC_KorC.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR NCBIfam; TIGR02175; PorC_KorC; 1.
DR PANTHER; PTHR43366; PYRUVATE SYNTHASE SUBUNIT PORC; 1.
DR PANTHER; PTHR43366:SF1; PYRUVATE SYNTHASE SUBUNIT PORC; 1.
DR Pfam; PF01558; POR; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Pyruvate {ECO:0000313|EMBL:QCC52755.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000296706}.
FT DOMAIN 10..174
FT /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01558"
SQ SEQUENCE 179 AA; 19074 MW; A9F7390343C243F5 CRC64;
MYAIRIHGRG GQGTVTLAQL LAQAGHEEGI WTQATPSFGV ERRGAPVEAY VRYSDEKITE
RSHVEQPDCV IVQDTSLLEY VDVTEGLEDD GILLVNTDAD PAAVDVDTDA DVITVDATEI
ALENLGRPIM NTALLGAFAG ATDKLSTGSL ESVITRKFAG EVGRKNVAAT TDAYTEVHA
//
