ID A0A4D6HGY2_9EURY Unreviewed; 894 AA.
AC A0A4D6HGY2;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=PAS domain S-box protein {ECO:0000313|EMBL:QCC52017.1};
GN ORFNames=DV733_12615 {ECO:0000313|EMBL:QCC52017.1};
OS Halapricum salinum.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halapricum.
OX NCBI_TaxID=1457250 {ECO:0000313|EMBL:QCC52017.1, ECO:0000313|Proteomes:UP000296706};
RN [1] {ECO:0000313|EMBL:QCC52017.1, ECO:0000313|Proteomes:UP000296706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBA1105 {ECO:0000313|EMBL:QCC52017.1,
RC ECO:0000313|Proteomes:UP000296706};
RX PubMed=30975999; DOI=.1038/s41467-019-09390-9;
RA Xiong L., Liu S., Chen S., Xiao Y., Zhu B., Gao Y., Zhang Y., Chen B.,
RA Luo J., Deng Z., Chen X., Wang L., Chen S.;
RT "A new type of DNA phosphorothioation-based antiviral system in archaea.";
RL Nat. Commun. 10:1688-1688(2019).
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DR EMBL; CP031310; QCC52017.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D6HGY2; -.
DR STRING; 1457250.GCA_000755225_00365; -.
DR KEGG; hsn:DV733_12615; -.
DR Proteomes; UP000296706; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08448; PAS_4; 2.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 3.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000296706};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 154..207
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 431..501
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 503..554
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 555..611
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 629..682
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 686..888
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 894 AA; 97814 MW; BF7A8DADD4010A84 CRC64;
MERFVRGFIS LLRNPSSMTD PVRLLVVDPV DGAFAERIGR LDDAFVTVAV ERLEDAMAAL
GGDHVHCVVC TDGFDRPDPV AVVGAIADGW PEIPVVVTAR DGSERLATDV LGAGATDYLP
LSDEDRLAER IWDALENQSG EPRTVETAVT SEGTPVPLES VAGSLSEVLV TIDEDSTVQY
VNDAVREVFG YDPAEVVGSS LTMLMPDRFH GPHHEGVARY LDTGDRALDW SSIELPGEHA
DGHEIDLEIS FGEFTVAGER HFTGLLRDVS PLVERETALS DLYEASDRLL LASTPEEIAE
ITAETASKAL DLPITGVYRH EPGLEALVPV ATTEQARALF GEPTLAAGES LAWETFENGE
TRVIRDVAEQ GPVHDPETDI RTELQVPVGD RWLLVSGSRE DRQFDDYQID FAELLSTTAA
AAFESAQREA ELRRYETIFE TIDARVAVLD ASGHVRMANQ ALCSFLGRSE DGVLGSSAAD
FVSEADAKRI RTRLGSLESG ESTTVEVTLT TADRSSVPCE VVFAPLPEAA QLNGVVAVVH
DISERREVES ELQHQRDRFV ELFENVPDPV VEATITDGKP IVESVNDAFE ETFGYDAERV
VGNSLNEFVL PPEEGDAGVD LDRKAAAGEL VSAEVRRETA GGIRYFLFRG IPVTSDDGEG
TPAFGVYTDI TDQRLRQRRL GVLNRVLRHN IRNDMSVVLG RANYLEETDD PDDLDTHAEA
IRRMAEDVVD LAEGIRTAEQ ALDREDAPSR PLATIIDQTV EPYRQREDTV VRTTVGGSLP
SIDERIGIVL EALIENAIEH GDREPTTVEI AVERPDHRIA IEVRDDGPGL PTEERTILER
QEETPLEHGQ GVGLWLVTWL VTSLGGDVEY ADNEPRGSIV RLSFPDNAVS WPEA
//
