ID A0A4D9DJV6_9SAUR Unreviewed; 841 AA.
AC A0A4D9DJV6;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Putative helicase with zinc finger domain {ECO:0000313|EMBL:TFJ97188.1};
GN ORFNames=DR999_PMT20996 {ECO:0000313|EMBL:TFJ97188.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFJ97188.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFJ97188.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFJ97188.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFJ97188.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFJ97188.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFJ97188.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFJ97188.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family. GABA-B
CC receptor subfamily. {ECO:0000256|ARBA:ARBA00008991}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFJ97188.1}.
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DR EMBL; QXTE01000522; TFJ97188.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9DJV6; -.
DR STRING; 55544.A0A4D9DJV6; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd15291; 7tmC_GABA-B-R1; 1.
DR CDD; cd06366; PBP1_GABAb_receptor; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR002455; GPCR3_GABA-B.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR002456; GPCR_3_GABA_rcpt_B1.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR PANTHER; PTHR10519:SF76; GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR01177; GABAB1RECPTR.
DR PRINTS; PR01176; GABABRECEPTR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:TFJ97188.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Helicase {ECO:0000313|EMBL:TFJ97188.1};
KW Hydrolase {ECO:0000313|EMBL:TFJ97188.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000313|EMBL:TFJ97188.1};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000297703};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..841
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5020032913"
FT TRANSMEM 445..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 521..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 562..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 622..642
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..680
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 686..708
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 452..730
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 719..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 719..738
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..784
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 841 AA; 95117 MW; 412FA4711FB55CD9 CRC64;
MRPAALLPLL LLTGWPLAAG RRAVHIGALF PMSGGWPGGQ ACLPAVRMAL EDVNRRRDIL
PDHELRLIHH DSKCDPGQAT KYLYELLYND PIKIILMPGC SSVSTLVAEA ARMWNLIVLS
YGSSSPALSN RQRFPTFFRT HPSATLHNPT RVQLFKKWGW TKIATIQQTT EVFTSTLDDL
DQRVKEAGIE ITFRQSFFSD PSAPVRSLKR QDARIIVGLF YETEARKVFC EVYKEKLYGK
RYVWFLIGWY ADNWFRIKDP AINCTEAEMA EAVEGHVTTE IVMLNPENTR SISNMTSQEF
IEKLQKRLGK NPEETGGFQE APLAYDAIWA LALALNKTSA ELVKKGLRLE DFNYNNKNIT
DEIYRALNSS AFEGVSGHVV FDASGSRMAW TLIEQLQGGV YKKIGYYDST KDNLSWYNND
KWIGDAPPAD YTKVITTFRF LSQKLFISVS VLASLGILLA IVCLAFNIYN GHVRYIQNSQ
PYLNNMTAVG CTLALAAVFP LGLDGYHIGS GLFPFVCQAR LWLLGLGFSL AYGSMFTKIW
WVHTVFTKKE EKKERRKTLE PWKLYATVGL LVGLDVVMLA VWQIVDPLHR TIEEFTKEEP
KTDIDVSILP QLEHCSSTKM NTWLGIFYGF KGLLLLLGIF LAYETKSVST EKINDHRAVG
MAIYNVAVLC LITAPVTMIL NSQQDAAFAF ASLAVVFSSY ITLVVLFVPK MRRLITRGEW
QSEQQDTMKT GSSTNNNEEE KSRLLEKENR ELEKIIAEKE ERVSELRQQL QDRQQLRSRR
RPSNPSSRDG CAADNHFTNA AVPVPTLYQP SLPLVRCLVS EQADKLGRSN CDGSRVHLLY
K
//
