ID A0A4D9DM25_9SAUR Unreviewed; 856 AA.
AC A0A4D9DM25;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Transcription factor SOX-17-like {ECO:0000313|EMBL:TFJ96042.1};
GN ORFNames=DR999_PMT22204 {ECO:0000313|EMBL:TFJ96042.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFJ96042.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFJ96042.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFJ96042.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFJ96042.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFJ96042.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFJ96042.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFJ96042.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, axon
CC {ECO:0000256|ARBA:ARBA00004489}. Cell projection, dendrite
CC {ECO:0000256|ARBA:ARBA00004279}. Secreted
CC {ECO:0000256|ARBA:ARBA00004613}. Synapse
CC {ECO:0000256|ARBA:ARBA00034103}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFJ96042.1}.
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DR EMBL; QXTE01000841; TFJ96042.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9DM25; -.
DR STRING; 55544.A0A4D9DM25; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0030424; C:axon; IEA:UniProtKB-SubCell.
DR GO; GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00017; ANATO; 1.
DR Gene3D; 1.50.10.20; -; 1.
DR Gene3D; 2.20.130.20; -; 1.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.40.1930; -; 1.
DR Gene3D; 2.60.40.1940; -; 1.
DR Gene3D; 1.20.91.20; Anaphylotoxins (complement system); 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR036595; A-macroglobulin_rcpt-bd_sf.
DR InterPro; IPR011626; Alpha-macroglobulin_TED.
DR InterPro; IPR000020; Anaphylatoxin/fibulin.
DR InterPro; IPR018081; Anaphylatoxin_comp_syst.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001599; Macroglobln_a2.
DR InterPro; IPR040839; MG4.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR PANTHER; PTHR11412:SF86; COMPLEMENT C4-A-RELATED; 1.
DR PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR Pfam; PF00207; A2M; 1.
DR Pfam; PF01821; ANATO; 1.
DR Pfam; PF17789; MG4; 1.
DR Pfam; PF01759; NTR; 1.
DR Pfam; PF07678; TED_complement; 1.
DR SMART; SM01360; A2M; 1.
DR SMART; SM00104; ANATO; 1.
DR SMART; SM00643; C345C; 1.
DR SUPFAM; SSF49410; Alpha-macroglobulin receptor domain; 1.
DR SUPFAM; SSF47686; Anaphylotoxins (complement system); 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR PROSITE; PS01178; ANAPHYLATOXIN_2; 1.
DR PROSITE; PS50189; NTR; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000297703};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Sulfation {ECO:0000256|ARBA:ARBA00022641};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT DOMAIN 281..318
FT /note="Anaphylatoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS01178"
FT DOMAIN 710..854
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT REGION 447..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 856 AA; 95902 MW; CC281A6F08ED0671 CRC64;
MGLFRAELWA RFSIRNQRFL PLSHFHFRVF ALNHELRPTA ESITITVLNN QGLQVRKVER
FPQNWVITDQ LSIPDIAEPG TWRITARFSN ALESNTSTEF EIVPERTHML VTGEGGPDLR
IDLQVRFVYG KGVNGVAYLR FGVSDEDGEK TFLRGLEQQV TDPYPFGTPL GSSSPCGELE
EQELSTVKFV TSPYSVDLSQ TKRHFIPGTP FLVLARVTLA DGSPAPRTPV WVSAEVSGGP
SHPERRVVAD ESGMVMFPLN LDSRASALTL KYQADPLALR CCRDGMTPVP MRRTCEQRAK
RILGPDADRC RGPFLDCCQF ATALRRKARA SVSGGLARVN PELDEDEFFD EDSVQTRSVF
PESWLWKTIT VKGSSWQTHL VPDSITTWEI QAVSMSPSTG ICVSDPLSVR VFQDFHVSLR
LPYAVKRFEQ LELRPVLYNY RDRPVNRTDR QTLVPPSPAR PRHEPRMEHE GGAGTEGYER
ILTFRKTDGS YGAWLHRASS TWLTAFVVKV LALSQQYQDV DSAGIRQSVT WLLGNQQADG
SFHDPQPVIH RDMQGGVGGH QGGVSLTAFV VVALKQGQTV YEGQEAEPQL QAEKQEQRER
VKSSLARATR YLSAAPEQGQ DPYPAAITAY ALSLASDDAA AIGAANRRLR DLAVQDNVDE
EDDYDYDYGG EAPAAEAPLH PIHWFDARRR RRREAADPGK RNKDVAYSVC IWRQPGSRLS
GMAIADITLL SGFQPHMDDL DKVQQLEELS GFRAYEAEIL EPLQFTEDVE LQAGQSRLFL
VRGSCRTRLV PSKRYLLMGQ DGETLDPQGR RRYLLDAAAW IEELPDPKRC QATAHRNRCA
QLRAFAQGYG QNGCKV
//
