ID A0A4D9DTW6_9SAUR Unreviewed; 228 AA.
AC A0A4D9DTW6;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Transmembrane emp24 domain-containing protein 1 {ECO:0000256|ARBA:ARBA00040024};
DE AltName: Full=p24 family protein gamma-1 {ECO:0000256|ARBA:ARBA00041274};
GN ORFNames=DR999_PMT19731 {ECO:0000313|EMBL:TFJ98322.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFJ98322.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFJ98322.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFJ98322.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFJ98322.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFJ98322.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFJ98322.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFJ98322.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004115}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004115}.
CC Endoplasmic reticulum-Golgi intermediate compartment membrane
CC {ECO:0000256|ARBA:ARBA00004151}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004151}. Golgi apparatus, cis-Golgi network
CC membrane {ECO:0000256|ARBA:ARBA00004619}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004619}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003827}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003827}.
CC -!- SIMILARITY: Belongs to the EMP24/GP25L family.
CC {ECO:0000256|ARBA:ARBA00007104, ECO:0000256|RuleBase:RU003827}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFJ98322.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QXTE01000407; TFJ98322.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9DTW6; -.
DR STRING; 55544.A0A4D9DTW6; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR015720; Emp24-like.
DR InterPro; IPR009038; GOLD_dom.
DR InterPro; IPR036598; GOLD_dom_sf.
DR PANTHER; PTHR22811; TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22811:SF40; TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF01105; EMP24_GP25L; 1.
DR SMART; SM01190; EMP24_GP25L; 1.
DR SUPFAM; SSF101576; Supernatant protein factor (SPF), C-terminal domain; 1.
DR PROSITE; PS50866; GOLD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000297703};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003827};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022927}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..228
FT /note="Transmembrane emp24 domain-containing protein 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5020025302"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..126
FT /note="GOLD"
FT /evidence="ECO:0000259|PROSITE:PS50866"
SQ SEQUENCE 228 AA; 25974 MW; EF2543B689628FC2 CRC64;
MMAAAWRALW WRLLLLLAPW GGSRAALPPP QDSEFTFLLP AGRRECFYQG APGNGSMEAE
FQVIGGAGLD IDFSLESPSG VLLINEYRKS DGVHTIEPTE AGDYKLCFDN SFSTISEKLV
FFELIFDSPQ EDEDGDNWAE VVEPEEMLDM KIEDIKESIE TMKNRLERSI QMQTLLRAFE
ARDRNLQESN MSRVNFWSAV NLGVLVVVAF LQVYMLKSLF EDKRQVRT
//
