ID A0A4D9E1I8_9SAUR Unreviewed; 1121 AA.
AC A0A4D9E1I8;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 22-FEB-2023, entry version 14.
DE SubName: Full=Sodium-and chloride-dependent GABA transporter 1-like {ECO:0000313|EMBL:TFK02058.1};
GN ORFNames=DR999_PMT15649 {ECO:0000313|EMBL:TFK02058.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFK02058.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFK02058.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK02058.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK02058.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFK02058.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK02058.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK02058.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the formin homology family.
CC {ECO:0000256|ARBA:ARBA00023449}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFK02058.1}.
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DR EMBL; QXTE01000201; TFK02058.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9E1I8; -.
DR STRING; 55544.A0A4D9E1I8; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014767; DAD_dom.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR043592; FMNL_animal.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR45857:SF2; FORMIN-LIKE PROTEIN 1; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 2.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51231; DAD; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000297703}.
FT DOMAIN 35..480
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 650..1041
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT DOMAIN 1075..1109
FT /note="DAD"
FT /evidence="ECO:0000259|PROSITE:PS51231"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1031..1054
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1089..1121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..566
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..634
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1121 AA; 125617 MW; B69D6F8F1DBFB96B CRC64;
MGNAAGSMDQ APAKETKTQP PATTLPAKQP VPPKQPMPSA GELEERFTHV LDSMNLPPDK
MKLLSQYDSE KKWELICDQE RFQVKNPPSA YIQKLKSYLD TGGVSRKVTS DWLIAMAFKR
RVQESTQVLR ELEISLRTNY IRWVQEFLNE ENKGLDVLLE YLAFAQCAVT YNMESADNGS
PGSDKGKSPD RSMEDLSKSN SSSPTQGSSK TRNLTIRLNP VHSRKAMRNS RIISQKDDVH
LCIMCLRAIM NYQSGFSLVM NHPACVNEIT LSLNNKNPRT KALVLELLAA VCLVRGGHDI
ILAAFDNFKE VCGEKNRFEK LMEYFRNEDS NIDFMVACMQ FINIVVHSVE NMNFRVFLQY
EFTHLGLDEY LERLRYTESD KLQVQIQAYL DNIFDVGALL EDTETKNAVL EHMEDLQEQV
GQLTEKLQDA ENESMAKIAE LEKQLSQTRR EVETLRERLS ESSSQASSPP QQQQQQQRLA
DARPSALEQK LEELEEKGLV RILRGPEGAV AIEIVPVVME TTAVPTVTVE AYASTSTDFA
SPSICSPLPP PAAAQTIPPP PPLPHTEDTG SANLPSQQQT QPSAPPPAPP LPGSDTPPPA
PPLPGVEIPP PPPLSVEGSP APPPPPPPPL GMPVGEVSGP TTAASSAVKI KKPIQTKFRM
PIFNWVALKP TQINGTIFNE LNDEKVLQEL DMNDFEEQFK TKAQGPSLDI STLKVKAVQK
APSKVTLIES NRAKNLAITL RKGGLSIDSI CKAIQTYDLQ SLSLDFLELL QRFLPTEYEL
TLIRKYEKEQ RPLEELSDED IFMIKFSQIP RLAEHMNIMT FLGNFSDTAQ LLMPQFNAII
AASMSLKSST KLRNILEIVL AFGNYTNSSK RGAAYGFRLQ SLDALLEMKS TDRKQTLLHY
IGRVIMEKYP ELTGFHTELH FLDKAGSVSL DSVLQDMRAL QRGMELTRKE FMRQDDSQVL
KDFLKANTEV MEKLQTDSKT AQEAYESAVE YFGENPKTSP PTMFFPIFVR FVKAYKKVEH
DIELWRKEEA AAKEVESNSP SKPEPKSPVH KAKRQQMDMI AELKKKQMVK EPLIYEGGDG
AIEDIISGLR NQPYRRGDTS RCSAKKRPTG QTLQVTSDIS L
//
