ID   A0A4D9E2P1_9SAUR        Unreviewed;      1890 AA.
AC   A0A4D9E2P1;
DT   03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   03-JUL-2019, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Malignant fibrous histiocytoma-amplified sequence 1 like protein {ECO:0000313|EMBL:TFK02518.1};
GN   ORFNames=DR999_PMT15200 {ECO:0000313|EMBL:TFK02518.1};
OS   Platysternon megacephalum (big-headed turtle).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Testudinoidea; Platysternidae; Platysternon.
OX   NCBI_TaxID=55544 {ECO:0000313|EMBL:TFK02518.1, ECO:0000313|Proteomes:UP000297703};
RN   [1] {ECO:0000313|EMBL:TFK02518.1, ECO:0000313|Proteomes:UP000297703}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DO16091913 {ECO:0000313|EMBL:TFK02518.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:TFK02518.1};
RA   Gong S.;
RT   "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL   Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:TFK02518.1, ECO:0000313|Proteomes:UP000297703}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DO16091913 {ECO:0000313|EMBL:TFK02518.1};
RC   TISSUE=Muscle {ECO:0000313|EMBL:TFK02518.1};
RA   Gong S.;
RT   "The genome sequence of big-headed turtle.";
RL   Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the APC1 family.
CC       {ECO:0000256|ARBA:ARBA00010547}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TFK02518.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QXTE01000187; TFK02518.1; -; Genomic_DNA.
DR   STRING; 55544.A0A4D9E2P1; -.
DR   Proteomes; UP000297703; Unassembled WGS sequence.
DR   GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR024990; Apc1.
DR   InterPro; IPR048971; Apc1_3rd.
DR   InterPro; IPR041221; APC1_C.
DR   InterPro; IPR046794; Apc1_MidN.
DR   InterPro; IPR049255; Apc1_N.
DR   InterPro; IPR011989; ARM-like.
DR   PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR   PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR   Pfam; PF12859; ANAPC1; 1.
DR   Pfam; PF21282; APC1_3rd; 1.
DR   Pfam; PF18122; APC1_C; 1.
DR   Pfam; PF20518; Apc1_MidN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000297703};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          84..204
FT                   /note="Anaphase-promoting complex subunit 1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12859"
FT   DOMAIN          669..987
FT                   /note="Anaphase-promoting complex subunit 1 middle"
FT                   /evidence="ECO:0000259|Pfam:PF20518"
FT   DOMAIN          1623..1708
FT                   /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF21282"
FT   DOMAIN          1742..1871
FT                   /note="Anaphase-promoting complex subunit 1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18122"
FT   REGION          309..352
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          376..398
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1890 AA;  210768 MW;  EC2BB8C7E8C56E4D CRC64;
     MSNNYEERVT MIAAGDLQEF VPFGRDHCKH HPNALNLQLR QLQPASELWS SDGAAGLVGS
     LQEVTIHEKQ KESWLLRRGV SDVGEEVEYD EELYVAGNMV IWSKGSKSQA SAVYKAFTVD
     SPVLQALWCD FTVPQEKSEK VDNSDEVVEK CICILQSSCI NVHSIEGKDY IASLPFQVAN
     VWPTKYGLLF ERSSTSHEVP LSPPREPLPT MFSMLHPLDE ITPLVCKSGA GVFGSARVQY
     VADYTLRIVF LNEEPSIVMT YDTVQSLHAV WALRRVKPEE QSTVLKFSEQ VGTPQHVATS
     SSLTAHLRSL SKGDSPMASP FQNYSSLHSQ SRSVSSPSVH SRSPSISNMA ALSRSHSPAL
     GVQSFSGVQR FNFSTNTQSP RRHNVSHSPN SASSDSFLAP ETEPIVPELC IDHLWTETIM
     TMREKNSQAS KVFITTDLCG QKFLCFLVES QLQLRCVKFQ ESNDKSQLIF GSVTNIQAKD
     AAPVESIDTL LVLEGNGNLV LYSGVVRVGK VFIPGLPAPS LTMSNQMPRP STPLDSLNTP
     SKPLNKHLGP LEEGVLLSPV PELRDSSKLH DSSYIDDCTF QQLGTFIHAV QDPVHNRVTL
     ELSNSSMVRI TIPEIATSEL VKRCLQGIKS ILPKEIAVQM LVKWYNAYNA PGGPSYHSEW
     SLFVTCLMNM MGYNTDRLAW TRNLDFEGSL SPVIAPKKAR PSETGSDEDW EYLLNSDYHR
     NLESHPLARA LRLDPLETSF PKDDFSPSLS LDSSTLLFTH IPAIFFVLHL IYEELKLNSL
     MGEGIRSLVV LLVQLARDLK LEAYIDYYYR EYPALVKTSR QTCIIDQAQT GFMHHPSFFS
     AEPPSIFQWL SSCLKGEGAL PYPYLPGICE RSKLVVLSVA LYILGDESAV SNEASHYLFR
     ITSGQRKQQA EQDDNRYSFR HSTSVSNLAE KLVIWMTSVG FTLRDLESLP FGVALPIRDA
     VYHCREQPAS DWPEAVCLLI GRQDLSKQAC EGNLAKGKSS VAQVLSSDVP SGAEAEEEDD
     GMNDMNQEVM SLIWSEDLRV QEVRRLLQSA HPVRVSVVQM PEVSDHEYIE EKENRLLQLC
     QRTMALPLGR GMFTLFSYHP VPTEPLPIPK LNLTGRAPPR NTTVDLNSGN IDVPPNMACW
     ASFHNGVAAG LKIAPASQID SAWIVYNKPK NAELANEYAG FLMALGLNGH LTKLATLNIH
     DYLTKGHEMT SIGLLLGVSA AKLGTMDMAI TRLLSIHIPA LLPPTSTELD VPHNVQVAAV
     IGIGLVYQRT AHRHTAEVLL AEIGRPPGPE MEYCTDRESY SLAAGLALGM VCLGHGSNLI
     GMSDLNVPEQ LYQYMVGGHK RFQAGMHREK HKSPSYQIKE GDTINVDVTC PGATLALAMI
     YLKTNNRSIA DWLRAPDTMY LLDFVKPEFL LLRTLARCLI LWDDILPNSK WVDSNVPQII
     RENSISLHAT ELPSSEDLNL ETLAQAHVYI IAGACLSLGF RFAGSENLAA FNCLFKFAKD
     FMKCLSAPTA SITGHYNLET CLSVVLLSLA MVMAGSGNLK VLQLCRFMHK KTGGEMNYGF
     HLAHHMALGL LFLGGGRYSL STSDSSIAAL LCALYPHFPV HSSDNRYHLQ ALRHLYVLAA
     EPRLLVPVDV DTNTPCYTLL EVTYKGTQWY EETTEELMAP TLLPELHLLK QIRVKGPRYW
     ELLIDLSKGT HQLKSILSKD GILYVKLRAG QLSYKEDPMG WRSLLAQAVT HRNSETRTFK
     PETISAFTSD PALLSFADYF CKPAVNMGQK QEILDLFSSI LYECVTRENP EMLPAYIAID
     QAVRILERKE MSETFELWQI KLVLEFFSSR SHQERVKRNP NRGLFMNSEF LPVMKCTIDN
     TLDQWLQGKE QHEYSATFWL RVCHPALGEI
//