ID A0A4D9E7P7_9SAUR Unreviewed; 915 AA.
AC A0A4D9E7P7;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 22-FEB-2023, entry version 13.
DE SubName: Full=Matrilin-2 {ECO:0000313|EMBL:TFK06349.1};
GN ORFNames=DR999_PMT10963 {ECO:0000313|EMBL:TFK06349.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFK06349.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFK06349.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK06349.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK06349.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFK06349.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK06349.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK06349.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFK06349.1}.
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DR EMBL; QXTE01000097; TFK06349.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9E7P7; -.
DR STRING; 55544.A0A4D9E7P7; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06893; PX_SNX19; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR037909; SNX19_PX.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF31; SORTING NEXIN-19; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000297703};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 95..276
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 522..652
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 330..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 682..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 767..797
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..348
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 694..712
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 915 AA; 101492 MW; 4DD34BB0CC3034D3 CRC64;
MENQRMLKTQ KSCASLGNGL SELVGNRKLM VLGALLAWLL VVHLLVNVWL LCLLSGLLAV
LGGWLGSQAV IGTHSRLHLE RFVLLESCPQ SPEAERQLDE EIDRMIQKII RDFVSSWYRT
VSSEQGFEDE VRKAMTGLAL ELKRRMALVD KQALTHKILL LCGCHLQSYM KARESMEAAR
SPAGPAQLAD QLWRAYSELS APHPAVQSPA MEVNYARSIV DLLLRVLVPK PHLETRTGRF
VVVELVTCNV LLPMIKKMSD PDWINLLLIG IFSKMGSKGV RRGKGEEPLL AASPCQPTVP
NSLPLKVVAP SPRPSELPSY DVVDSLECNP QEAEEGKDLT RGEPGADVDG RKAGSTPVHY
PQPDTLGSLF LCEDSELESP MSDFGKDSDS VVLLSTEEFL TDTFQDSFAV LEGPDGLDQE
DGVVAKDGYL EESTETSVLP SALGQCPDIQ IDPAVEKEES LASVTALLAD PEKPFSRRPS
FLENPAKSPL DPSQPPLPLY SSHTFSFEPL SSPDSPIIIQ NLRITGTITA REHSGTGFHP
YTLYTVKYET ALESENANNL QQVAYHTVNR RYREFLNLQT RLEEKPELRK FVKNVKGPKK
LFPDLPFGNM DSDKVEARKS LLESFLKQLC SIPEIANSEQ VQEFLALNTD ARIAFVKKPF
VVSRIDKIVL NAIVDTLKTA FPRSEPQSPT EELSEAEVDG KSQTDGKKAN KPRLRFPSSK
IAPVLSVAEA HERILYGLRE GSTVSDALSL GGMESFIQKQ EKLLEATSSE APETKGAGPT
HVPQQPVRQK DDPGSETPLA DMALDLLHLL LMDRWSWLCT ENMQKVLHLL FGSLIERWLE
VQVTNLTCTQ RWVQYLRLLQ ESIWPGGVLP AVPKPFRTQE QKEATAQQAL QSLMGLLPAA
VWSTPEVAAF QKWVK
//
