ID A0A4D9EAW2_9SAUR Unreviewed; 902 AA.
AC A0A4D9EAW2;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=GAS2-like protein 3 {ECO:0000313|EMBL:TFK04503.1};
GN ORFNames=DR999_PMT12972 {ECO:0000313|EMBL:TFK04503.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFK04503.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFK04503.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK04503.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK04503.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFK04503.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK04503.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK04503.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFK04503.1}.
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DR EMBL; QXTE01000136; TFK04503.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9EAW2; -.
DR STRING; 55544.A0A4D9EAW2; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd07619; BAR_Rich2; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR047165; RHG17/44/SH3BP1-like.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR14130; 3BP-1 RELATED RHOGAP; 1.
DR PANTHER; PTHR14130:SF13; RHO GTPASE-ACTIVATING PROTEIN 44; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000297703}.
FT DOMAIN 14..249
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 255..445
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 464..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 527..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 730..902
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..490
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..549
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..652
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 730..770
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 790..804
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 833..859
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..875
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 876..902
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 902 AA; 98864 MW; 149E7C0CF90B1EFC CRC64;
MKKQFNRMRQ LANQTVGRAE KTEVLSEDLL QVEKRLELVK QVSHSTHKKL TACLQGQQGV
DADKRSKKLP LTTLAQCLME GSAILGDDSL LGKMLKLCGE AEDKLAQELI HFELEVERDV
IDPLFVLAEV EIPNIQKQRK HLAKLVLDMD SSRTRWQQSA KSSGLSSNLQ PSGAKADALR
EEMEEAANRV EICRDQLSAD MYNFVAKEID YANYFQTLIE VQAEYHRKSL ALLQNVLPQI
KAQQEAWIEK PSFGKSLEEH LAVSGREIAF PIEACITMLL ECGMQEEGLF RVAPSASKLK
KLKAALDCCV VDVQEYSADP HAIAGALKSY LRELPEPLMT FELYDEWIQA SNIQDQDKRL
QALWNACEKL PKANYNNIRY LIKFLAKLTE YQDANKMTPS NVAIVLGPNL LWPQAEGNIT
EMMTTVSLQI VGIIEPLIQH ADWFFPGDIE FNVTGNYGSP MHVNHNANYS SMPSPDMDHS
DRKQHDQARR PLSVATDNMM LEFYKKDGMG VRVMDTSWVA RRGTTIVRKA SSTPPAMQPP
APPSDLAATP QSPIPEQSLD ISATPSPTPT SFGFQPGAER TSTDDVSSSW LDSCYHYPSP
EDDRPPPYPC YQHLRHYHPQ ARPEAPSPPY RWSGHSQTLP PRSSSSPSPQ PLDINSNPKP
CFLHLPKQSS LTESHALETN LSAPSIKPPL VLAKPDPPGA PYPSLMSASP PWVGCASDRG
AGLTSTLKTK ELSPVSGQKG SPSSCHVAPC GSMQQVASPT QQLSTEQSPH ALRKVSKKLA
PITPKVPYGQ SGGMSDQSTG QPSPVSLSPT PPSTPSPYGL NYPHGYSLAS GQLSPAAAPS
LSSPPSLTST LTKSRPTPKP RQRPTLPPPQ PPTASLTGAS PQSMDHTLLD DMSPGESMST
AV
//
